Phys 10. 채 준()

STUDY(THESIS)

1. 4(Sun)

Self-Assembly of Symmetric Finite-Size DNA Nanoarrays - Yan Liu, Yonggang Ke, and Hao Yan

http://pubs.acs.org/doi/pdf/10.1021/ja055614o

• The one task that Structural DNA nanotechnology has is to control the size of DNA self-assembly

1. To produce effectively fixed-size DNA arrays, we need to use the geometric symmetry of DNA arrays with Cm symmetry.
2. Because of the geometric symmetry, the higher number m is, the fewer DNA tiles we need.

• In the thesis they show the 5*5 DNA arrays that has C2 symmetry and C4 symmetry

1. In C2 symmetry, the array needs 13 tiles instead of 25 tiles.
2. In C4 symmetry, the array needs 7 tiles instead of 25 tiles.
3. In C4 symmetry, the array is composed of crosslike DNA tiles. A cross-shaped DNA tile has a flexibility under a stress.

[from the thesis, DOI:10.1021/ja055614o]

-The Ex. of C2 symmetry. Because of geometric symmetry, the array has the same DNA tiles in it in each a half round.

• what I felt

-This strategy maybe could help to construct the larger fixed-size DNA Structure than ever before.