Fanglab:Publications
FANG LABORATORY
The Methodist Hospital Research Institute, Houston, Texas.
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Fanglab
2021
Systemic metabolite profiling reveals sexual dimorphism of AIBP control of metabolism in mice. Kim JD, Zhu L, Sun Q, Fang L. PLoS One. 2021 Apr 1;16(4):e0248964. doi: 10.1371/journal.pone.0248964. eCollection 2021. PMID: 33793635
2020
Combination of apolipoprotein-A-I/apolipoprotein-A-I binding protein and anti-VEGF treatment overcomes anti-VEGF resistance in choroidal neovascularization in mice. Zhu L, Parker M, Enemchukwu N, Shen M, Zhang G, Yan Q, Handa JT, Fang L, Fu Y. Commun Biol. 2020 Jul 16;3(1):386. doi: 10.1038/s42003-020-1113-z. PMID: 32678293
Hematopoiesis is regulated by cholesterol efflux pathways and lipid rafts: connections with cardiovascular diseases. Morgan PK, Fang L, Lancaster GI, Murphy AJ. J Lipid Res. 2020 May;61(5):667-675. doi: 10.1194/jlr.TR119000267. Epub 2019 Aug 30. PMID: 31471447
2019
Regulation of lipid rafts, angiogenesis and inflammation by AIBP. Fang L, Miller YI. Curr Opin Lipidol. 2019 Jun;30(3):218-223. doi: 10.1097/MOL.0000000000000596. PMID: 30985364
1.AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, Traver D, Cooke JP, Li W, Zon LI, Chen K, Bai Y, Fang L. Science. 2019 Jan 31. pii: eaav1749. doi: 10.1126/science.aav1749. [Epub ahead of print] PMID: 30705153
2018
1.TBX20 Regulates Angiogenesis Through the Prokineticin 2-Prokineticin Receptor 1 Pathway. Meng S, Gu Q, Yang X, Lv J, Owusu I, Matrone G, Chen K, Cooke JP, Fang L. Circulation. 2018 Aug 28;138(9):913-928. doi: 10.1161/CIRCULATIONAHA.118.033939. PMID: 29545372
2.AIBP protects against metabolic abnormalities and atherosclerosis. Schneider DA, Choi SH, Agatisa-Boyle C, Zhu L, Kim J, Pattison J, Sears DD, Gordts PLSM, Fang L, Miller YI. J Lipid Res. 2018 May;59(5):854-863. doi: 10.1194/jlr.M083618. Epub 2018 Mar 20. PMID: 29559522
3. AIBP augments cholesterol efflux from alveolar macrophages to surfactant and reduces acute lung inflammation. Choi SH, Wallace AM, Schneider DA, Burg E, Kim J, Alekseeva E, Ubags ND, Cool CD, Fang L, Suratt BT, Miller YI. JCI Insight. 2018 Aug 23;3(16). pii: 120519. doi: 10.1172/jci.insight.120519. [Epub ahead of print] PMID: 30135304
2017
1. AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling. Mao R, Meng S, Gu Q, Araujo-Gutierrez R, Kumar S, Yan Q, Almazan F, Youker KA, Fu Y, Pownall HJ, Cooke JP, Miller YI, Fang L. Circ Res. 2017 Mar 21. pii: CIRCRESAHA.116.309754. doi: 10.1161/CIRCRESAHA.116.309754. [Epub ahead of print] PMID: 28325782
2015
1. Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia. Liu C, Gates KP, Fang L, Amar MJ, Schneider DA, Geng H, Huang W, Kim J, Pattison J, Zhang J, Witztum JL, Remaley AT, Dong PD, Miller YI. Dis Model Mech. 2015 Aug 1;8(8):989-98. doi: 10.1242/dmm.019836. Epub 2015 Jun 4. PMID:26044956
2. Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development. Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC. Dev Biol. 2015 Aug 15;404(2):49-60. doi: 10.1016/j.ydbio.2015.05.011. Epub 2015 May 22. PMID:26004360
3. Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a. Chen Z, Wen L, Martin M, Hsu CY, Fang L, Lin FM, Lin TY, Geary MJ, Geary GG, Zhao Y, Johnson DA, Chen JW, Lin SJ, Chien S, Huang HD, Miller YI, Huang PH, Shyy JY. Circulation. 2015 Mar 3;131(9):805-14. doi: 10.1161/CIRCULATIONAHA.114.013675. Epub 2014 Dec 30. PMID:25550450
2014
1. Zebrafish models of dyslipidemia: relevance to atherosclerosis and angiogenesis. Fang L, Liu C, Miller YI. Transl Res. 2014 Feb;163(2):99-108. doi: 10.1016/j.trsl.2013.09.004. Epub 2013 Oct 2. Review. PMID:24095954
2013
1. Targeted cholesterol efflux. Fang L, Miller YI. Cell Cycle. 2013 Nov 1;12(21):3345-6. doi: 10.4161/cc.26401. Epub 2013 Sep 13. No abstract available. PMID:24036659
2. Control of angiogenesis by AIBP-mediated cholesterol efflux. Fang L, Choi SH, Baek JS, Liu C, Almazan F, Ulrich F, Wiesner P, Taleb A, Deer E, Pattison J, Torres-Vázquez J, Li AC, Miller YI. Nature. 2013 Jun 6;498(7452):118-22. doi: 10.1038/nature12166. Epub 2013 May 29. PMID:23719382
2012
1. Emerging applications for zebrafish as a model organism to study oxidative mechanisms and their roles in inflammation and vascular accumulation of oxidized lipids. Fang L, Miller YI. Free Radic Biol Med. 2012 Oct 1;53(7):1411-20. doi: 10.1016/j.freeradbiomed.2012.08.004. Epub 2012 Aug 11. Review. PMID:22906686
2. Ezetimibe and simvastatin reduce cholesterol levels in zebrafish larvae fed a high-cholesterol diet.
Baek JS, Fang L, Li AC, Miller YI.
Cholesterol. 2012;2012:564705. doi: 10.1155/2012/564705. Epub 2012 May 30.
PMID:22693663
2011
1. In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish. Fang L, Green SR, Baek JS, Lee SH, Ellett F, Deer E, Lieschke GJ, Witztum JL, Tsimikas S, Miller YI. J Clin Invest. 2011 Dec;121(12):4861-9. doi: 10.1172/JCI57755. Epub 2011 Nov 21. PMID:22105168
2. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. Circ Res. 2011 Jan 21;108(2):235-48. doi: 10.1161/CIRCRESAHA.110.223875. Review. PMID:21252151
2010
1. Oxidized cholesteryl esters and phospholipids in zebrafish larvae fed a high cholesterol diet: macrophage binding and activation. Fang L, Harkewicz R, Hartvigsen K, Wiesner P, Choi SH, Almazan F, Pattison J, Deer E, Sayaphupha T, Dennis EA, Witztum JL, Tsimikas S, Miller YI. J Biol Chem. 2010 Oct 15;285(42):32343-51. doi: 10.1074/jbc.M110.137257. Epub 2010 Aug 14. PMID:20710028
2. Toll-like receptor-4 and lipoprotein accumulation in macrophages. Miller YI, Choi SH, Fang L, Harkewicz R. Trends Cardiovasc Med. 2009 Oct;19(7):227-32. doi: 10.1016/j.tcm.2010.02.001. Review. PMID:20382346
3. Lipoprotein modification and macrophage uptake: role of pathologic cholesterol transport in atherogenesis. Miller YI, Choi SH, Fang L, Tsimikas S. Subcell Biochem. 2010;51:229-51. doi: 10.1007/978-90-481-8622-8_8. Review. PMID:20213546
2009
1.Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins. Yang G, Li Q, Ren S, Lu X, Fang L, Zhou W, Zhang F, Xu F, Zhang Z, Zeng R, Lottspeich F, Chen Z. Proteomics. 2009 Nov;9(21):4944-61. doi: 10.1002/pmic.200800762. PMID:19743411
2.Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish. Stoletov K, Fang L, Choi SH, Hartvigsen K, Hansen LF, Hall C, Pattison J, Juliano J, Miller ER, Almazan F, Crosier P, Witztum JL, Klemke RL, Miller YI. Circ Res. 2009 Apr 24;104(8):952-60. doi: 10.1161/CIRCRESAHA.108.189803. Epub 2009 Mar 5. PMID:19265037
2008
1.Proteome identification of binding-partners interacting with cell polarity protein Par3 in Jurkat cells. Zhou Y, Fang L, Du D, Zhou W, Feng X, Chen J, Zhang Z, Chen Z. Acta Biochim Biophys Sin (Shanghai). 2008 Aug;40(8):729-39. PMID:18685789
2007
1.Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair. Fang L, Wang Y, Du D, Yang G, Tak Kwok T, Kai Kong S, Chen B, Chen DJ, Chen Z. Cell Res. 2007 Feb;17(2):100-16. Erratum in: Cell Res. 2007 Jun;17(6):572-4. PMID:17287830
2006
1.Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling. Wang Y, Du D, Fang L, Yang G, Zhang C, Zeng R, Ullrich A, Lottspeich F, Chen Z. EMBO J. 2006 Nov 1;25(21):5058-70. Epub 2006 Oct 19. PMID:17053785
