BME100 f2013:W1200 Group5 L2

From OpenWetWare

Jump to: navigation, search
BME 100 Fall 2013 Home
People
Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3
Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6
Course Logistics For Instructors
Photos
Wiki Editing Help
Image:BME494_Asu_logo.png


Contents

OUR TEAM

Name: Dominick CocciolaRole(s)
Name: Dominick Cocciola
Role(s)
Name: Estefania MezaRole(s)
Name: Estefania Meza
Role(s)
Name: Hany ArafaRole(s)
Name: Hany Arafa
Role(s)
Name: Kristina RoscherRole(s)
Name: Kristina Roscher
Role(s)
Name: Wendy GrayRole(s)
Name: Wendy Gray
Role(s)

LAB 2 WRITE-UP

Descriptive Statistics

Human Study
Average:
0mg 3.545714286 pg/ml
5mg 8.932 pg/ml
10mg 61.622 pg/ml
15mg 657.941 pg/ml

Standard Deviation:
0mg 1.523010177 pg/ml
5mg 1.593931547 pg/ml
10mg 30.11069386 pg/ml
15mg 212.9429762 pg/ml

Standard Error
0mg 0.48161811 pg/ml
5mg 0.50404541 pg/ml
10mg 9.52183745 pg/ml
15mg 67.3384817 pg/ml

Median
0mg 4.12 pg/ml
5mg 8.98 pg/ml
10mg 73.395 pg/ml
15mg 722.505 pg/ml

Mode
The mode does not exist because none of the results from each trial were the same.

Rat Study
Average:
0mg 10.516 pg/ml
10mg 11.112 pg/ml

Standard Deviation:
0mg 2.225551617 pg/ml
10mg 7.402885924 pg/ml

Standard Error
0mg 0.99529694 pg/ml
10mg 3.31067123 pg/ml

Median
0mg 9.24 pg/ml
10mg 8.99 pg/ml

Mode
The mode does not exist because none of the results from each trial were the same.




Results

Human Study
Image:GRAPH 1.JPG
Rat Study

Image:5graph2b.jpg




Analysis

Experiment 1

Anova Test: P value = 1.40083E-16

Bonferroni Corection: 8.33E-03

Post-Hoc Test T-Tests Corrected P-Value Is it Significant
0 mg vs. 5 mg 8.59631E-07 8.33E-03 Yes
0 mg vs. 10 mg 9.94377E-06 8.33E-03 Yes
0 mg vs. 15 mg 1.39436E-08 8.33E-03 Yes
5 mg vs. 10 mg 3.01859E-05 8.33E-03 Yes
5 mg vs. 15 mg 1.57101E-08 8.33E-03 Yes
10mg vs. 15 mg 6.4824E-08 8.33E-03 Yes

Experiment 2

T-test on the rat data: p= 0.867403497
Image:Pvalue_(2).jpg
Running an ANOVA on the rat data yields the same results: Image:capture.jpg

Summary/Discussion

Experiment 1

The p value for experiment 1 is statistically significant, as shown in the t-test and graph of the humans trials. This means that there is a significant effect of LPS on the Inflammotin protein between 0 mg and 10 mg in humans. By checking all the possible t-tests with the corrected p values, all the t-tests prove that there is a significant effect of LPS and dose.

Experiment 2

The p value for experiment 2 is not statistically significant, as shown in the t-test and graph of the rat trials. This means there is not a significant effect of LPS on the Inflammotin protein between 0mg and 10mg in rats.







Personal tools