X:Research: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
No edit summary
No edit summary
(28 intermediate revisions by 2 users not shown)
Line 3: Line 3:
<center>
<center>
<font face="Helvetica" size=6 color=#339900>
<font face="Helvetica" size=6 color=#339900>
'''X-Laboratory'''  </font> <br>  
'''Synthetic Electrophysiology of Ion Channels'''  </font> <br>  
(Under Development) <br>
 
 
Principle Investigator: [http://openwetware.org/wiki/User:Xiaodong_Liu Xiaodong Liu, Ph.D.]
Principle Investigator: [http://openwetware.org/wiki/User:Xiaodong_Liu Xiaodong Liu, Ph.D.]
<br>
<br>


[http://bme.med.tsinghua.edu.cn Department of Biomedical Engineering] at [http://www.tsinghua.edu.cn/eng/index.jsp Tsinghua University]
[http://bme.med.tsinghua.edu.cn Department of Biomedical Engineering] at [http://www.med.tsinghua.edu.cn School of Medicine], [http://www.tsinghua.edu.cn/eng/index.jsp Tsinghua University]
</center>
</center>
----
----
Line 35: Line 36:
|width=800px class="MainPageBG" style="border: 0px solid #CC3300; background-color: #ffffff"|
|width=800px class="MainPageBG" style="border: 0px solid #CC3300; background-color: #ffffff"|
<font face="Helvetica" size=4>
<font face="Helvetica" size=4>
Research Projects
 
To apply '''engineering principles''' onto both '''biological''' entities (synthetic ion channels & modulators etc.) and '''physical''' components (electrical & optical materials, devices, instruments, etc.) exogenously coupled with excitable membranes of the cell for the
'''''re-constitution''''' of ion channels’ functions & pathophysiology.
</font><br>
</font><br>


<font face="Helvetica" size=3>
<font face="Helvetica" size=3>


1. Sensory signaling via channel complex (''e.g.'', TRP/GPCR or Ca<SUB>V</SUB>/CaM). <br>
 
2. Novel modulators of Ca<SUP>2+</SUP> channels as tools to pursue molecular physiology.<br>
3. Design and application of genetically encoded (optical) sensors.<br>
4. Mechanisms and engineering of membrane nanoporation.<br>




</font>
</font>
|}
|}

Revision as of 20:14, 22 October 2013


Synthetic Electrophysiology of Ion Channels


Principle Investigator: Xiaodong Liu, Ph.D.

Department of Biomedical Engineering at School of Medicine, Tsinghua University



To apply engineering principles onto both biological entities (synthetic ion channels & modulators etc.) and physical components (electrical & optical materials, devices, instruments, etc.) exogenously coupled with excitable membranes of the cell for the re-constitution of ion channels’ functions & pathophysiology.