X:Courses
2012 Spring-I
PTN清华进展和讨论生物学专题讨论之细胞膜离子通道基础专题模块 (2012 Spring)
上课时间：3/6；3/8；3/13；3/15 上午8:50-10:35 上课地点：清华 六教 6B308
Contact Info: Xiaodong Liu (刘晓冬), Ph.D. Professor of Biomedical Engineering and Life Sciences Principle Investigator of X-Lab http://openwetware.org/wiki/X-Lab School of Medicine Tsinghua University B-307 (office); B-229(Lab) Voice: (86)10-62796733 (O);
TA: 秦 毅（2011级PTN学生） 邮箱：ptnqyi@126.com 手机：18210604223
Lecture I （3/6) : Fundamentals of Ion Channels
a. Current Understanding: Permeation; Selectivity; Gating
b. Historical Retrospects
c. Molecular Physiology of Ion Channels (Molecular Biophysics & Pathophysiological Relevance)
Lecture II (3/8) : Quantitative Descriptions o of Ion Channel Behaviors
a. H-H, (see http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1392413/pdf/jphysiol01442-0106.pdf)
b. Single Channels (see http://openwetware.org/images/1/18/Paper_Neher_Lecture.pdf)
c. Simulations (see http://www.neuron.yale.edu/neuron/)
Lecture III (3/13): Frontiers of Ion Channels -I
a. Molecular Aspects
Paper A: http://www.nature.com/nature/journal/v451/n7180/full/nature06529.html
Paper B: http://www.nature.com/nature/journal/v463/n7283/full/nature08766.html
b. Comments, Insights and Beyond (for non-channel proteins, see http://bernstein.harvard.edu/papers/peter_science_1998.pdf)
Lecture IV (3/15): Frontiers of Ion Channels -II
a. Physiological Aspects
Paper C: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature10812.html
Paper D: http://www.nature.com/nature/journal/v447/n7148/full/nature05865.html
b. Comments, Insights and Beyond (optogenetics, see http://en.wikipedia.org/wiki/Optogenetics)
c. Brief Summary
2012 Spring-II
医学药学实验班 生理学之神经生理I (2012 Spring)
2012.5.15 五 2 三教1209 sensory functions I
2012.5.28 二 3 三教1209 sensory functions II
Textbook: medical physiology chapter 31
2012 Fall-I
生物医学工程系本科 神经工程模块 (2012 Fall)
神经科学与神经工程基础，3学分，三上
（研究生秋季学期）
召集人: 刘晓冬
主讲： 刘晓冬、宋森
神经科学与神经工程基础 (2012秋季)
Foundations of Neural Science & Engineering
(Fall 2012) 60 (48+12)
上课时间: 每周三上午3小时 上课地点：清华大学 （教室:)
讨论课时间: 周六,下午2小时 上课地点：清华大学 医学院 （教室待定)
课程负责人: 刘晓冬 <liuxiaodong@tsinghua.edu.cn>， 宋森 <sen.song@gmail.com>
助教:
教材：Foundations of Cellular Neurophysiology (Johnson and Wu, Q42 FJ72); Principles of Neural Sciences (Eric Kandel, R338 FP95);
参考书：Ion Channels of Excitable Membrane (Bertil Hille); Neural Engineering (2008, CRC Press, Q42 FN497); Neuroscience (Dale Purves, ISBN 978-0878936977, 医学馆) ; Neural Engineering (ISBN: 0585444684, MIT Press)
E-resource: Principles of Neural Sciences; Ion Channels of Excitable Membrane; Neuroscience
(Syllabus)
Introduction to Science and Engineering of Neural System
Course Coverage and General Introduction (1) Liu
(basic principles, quantitative bend, engineering emphasis)
Neural System: Molecular, Cellular; (1) Liu Circuit and System. (1) Song
Discussion I. Liu and Song
Neuronal Excitability
Electrical Properties of Neural Membrane: Membrane and HH Analysis (1) Liu
Ion Channels: Diversity and Physiology; Structure-Function: Single-Channel Analysis (2) Liu
Discussion II. Liu
Realistic Neuron, pre- and post-synaptic mechanisms (2) Song
Cable Equation (1) Song
Neural Stimulation (1) Song
Discussion III. Song
Functions of Nervous System
Sensory and Motor (3) Liu
Discussion IV. Liu
Cognitive: Learning, Memory and Emotion. (3) Song
Discussion V. Song
Discussion VI. Liu and Song
2012 Fall-II
可兴奋细胞膜之离子通道
生物医学工程系 研究生选修课 (2012 Fall)
