Wikiomics:Genome annotation

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m (Eukariota, genomic level))
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"""The Conrad gene caller is tool for predicting gene structures in DNA based on the DNA sequence and other available evidence. The gene caller uses semi-Markov Conditional Random Fields. The Conrad CRF engineis a general purpose CRF engine used by the gene caller to provide the structure and algorithms for gene calling."""
"""The Conrad gene caller is tool for predicting gene structures in DNA based on the DNA sequence and other available evidence. The gene caller uses semi-Markov Conditional Random Fields. The Conrad CRF engineis a general purpose CRF engine used by the gene caller to provide the structure and algorithms for gene calling."""
 +
* SNAP from Ian Korf: ik1@sanger.ac.uk
 +
Korf, Ian. “Gene finding in novel genomes.” BMC Bioinformatics 5, no. 1 (2004): 59.
===Prokaryots===
===Prokaryots===
* Bremen pipeline described in [http://www.pnas.org/cgi/content/full/100/14/8298 PNAS]
* Bremen pipeline described in [http://www.pnas.org/cgi/content/full/100/14/8298 PNAS]
* [http://www.megx.net/jcoast/index.php?navi=about JCOAST ] "java based program for comparative genomics working on top of GenDB v2.2 projects".
* [http://www.megx.net/jcoast/index.php?navi=about JCOAST ] "java based program for comparative genomics working on top of GenDB v2.2 projects".

Revision as of 13:48, 20 February 2008

Genome annotation process of finding functional (genes, regulatory elements, ncRNAs) and non-functional features (repeats) in the genomic sequence.

Contents

Gene finding

Comparative

Side issue: accurate cross-species genomic alignments

  • GRAPe GRAPe is a tool for computing genome re-alignment using marginalized posterior decoding.

Eukariota

Prokariota

  • GLIMMER

de novo

  • Jigsaw meta-program designed to use the output from gene finders, splice site prediction programs and sequence alignments to predict gene models.


Eukariota, genomic level)

"""The Conrad gene caller is tool for predicting gene structures in DNA based on the DNA sequence and other available evidence. The gene caller uses semi-Markov Conditional Random Fields. The Conrad CRF engineis a general purpose CRF engine used by the gene caller to provide the structure and algorithms for gene calling."""

  • SNAP from Ian Korf: ik1@sanger.ac.uk

Korf, Ian. “Gene finding in novel genomes.” BMC Bioinformatics 5, no. 1 (2004): 59.

Prokaryots

  • Bremen pipeline described in PNAS
  • JCOAST "java based program for comparative genomics working on top of GenDB v2.2 projects".
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