Week 9 Individual Journal William P Fuchs

In Class Activity

Purpose

To discover and implement various amino acid tools for the analysis and reconstruction of the protein structures of HIV.

Methods

1. Convert a nucleic acid sequence to a protein

• How do you know which of the six frames is the correct reading frame (without looking up the answer)?
  • 5'3' Frame 1 was the correct sequence because there was no stop codon in the reading frame.
• Check the derived sequence with the actual data set to test the accuracy of the read.

1. Investigate gp120 further and find entries for that protein

• If you search on the keywords "HIV" and "gp120", in the main UniProt search field, how many results do you get?
  • I got 206,278 hits
• Use the accession number "P04578" to narrow the search

Data and Files

• This figure presents multiple reading frames of one of Subject 10's clones

Acknowledgements

I worked with Matt Oki in developing the scope and direction of the amino acid project as well as developing the question, prediction and subject selection sections. While I worked with the people noted above, this individual journal entry was completed by me and not copied from another source.William P Fuchs 18:18, 25 October 2016 (EDT)

References

• Week 9 Assignment Page
  • Provided guidelines and instructions for this week's individual journal.

Externals

Individual Journals

• WPF Week 2
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• WPF Week 4
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Class Journals

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Assignments

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• Week 10
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• Week 14
• Week 15

Useful Links

1. Bio Class Page
2. BIOL368/F16:People
3. Will Fuchs
4. Link to LMU: http://www.lmu.edu/