User:Yiannis Kaznessis: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
Line 4: Line 4:
----
----
==Contact Info==
==Contact Info==
[[Image:OWWEmblem.png|thumb|right|Yiannis Kaznessis (an artistic interpretation)]]
[[Image:OWWEmblem.png|thumb|right|]]


*Yiannis Kaznessis
*Yiannis Kaznessis
Line 15: Line 15:
In my group we are interested in computational synthetic biology. We are developing the Synthetic Biology Software Suite, a publicly available software suite that assists in rationally designing synthetic gene regulatory networks.  
In my group we are interested in computational synthetic biology. We are developing the Synthetic Biology Software Suite, a publicly available software suite that assists in rationally designing synthetic gene regulatory networks.  


In recent work, we developed multiscale models of gene regulatory networks with synthetic biology applications. Simulations have been used that model all biomolecular interactions in transcription, translation, regulation, and induction of gene regulatory networks, guiding the design of synthetic systems. <ref> Y. N. Kaznessis, (2007) "Models for Synthetic Biology", BMC Systems Biology, 2007, 1:47 doi:10.1186/1752-0509-1-47 [http://www.biomedcentral.com/1752-0509/1/47]. </ref>
In recent work, we developed multiscale models of gene regulatory networks with synthetic biology applications. Simulations have been used that model all biomolecular interactions in transcription, translation, regulation, and induction of gene regulatory networks, guiding the design of synthetic systems.
<ref> Sotiropoulos V, Kaznessis YN. Synthetic tetracycline-inducible regulatory networks: computer-aided design of dynamic phenotypes. BMC Syst Biol. 2007 Jan 9;1:7.</ref>
<ref> Salis H, Kaznessis YN. Computer-aided design of modular protein devices: Boolean AND gene activation. Phys Biol. 2006 Dec 22;3(4):295-310.</ref>
<ref> Tomshine J, Kaznessis YN. Optimization of a stochastically simulated gene network model via simulated annealing. Biophys J. 2006 Nov 1;91(9):3196-205.</ref>


==Education==
==Education==

Revision as of 19:27, 7 July 2008

I am a new member of OpenWetWare!



Contact Info

  • Yiannis Kaznessis
  • Department of Chemical Engineering and Materials Science
  • University of Minnesota
  • 421 Washington Ave SE
  • Minneapolis, MN 55455, USA
  • Email me through OpenWetWare

In my group we are interested in computational synthetic biology. We are developing the Synthetic Biology Software Suite, a publicly available software suite that assists in rationally designing synthetic gene regulatory networks.

In recent work, we developed multiscale models of gene regulatory networks with synthetic biology applications. Simulations have been used that model all biomolecular interactions in transcription, translation, regulation, and induction of gene regulatory networks, guiding the design of synthetic systems.

Education

  • Year, PhD, Institute
  • Year, MS, Institute
  • Year, BS, Institute

Research interests

  1. Interest 1
  2. Interest 2
  3. Interest 3

Publications

  1. Goldbeter A and Koshland DE Jr. An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6840-4. DOI:10.1073/pnas.78.11.6840 | PubMed ID:6947258 | HubMed [Paper1]
  2. JACOB F and MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318-56. DOI:10.1016/s0022-2836(61)80072-7 | PubMed ID:13718526 | HubMed [Paper2]

    leave a comment about a paper here

  3. ISBN:0879697164 [Book1]

All Medline abstracts: PubMed | HubMed

Useful links