User:Xiaosai Yao: Difference between revisions
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<!-- Feel free to add brief descriptions to your research interests as well --> | <!-- Feel free to add brief descriptions to your research interests as well --> | ||
I am interested in developing cancer therapeutics using protein engineering, in particular affinity maturation with yeast surface display developed by the Wittrup lab. I design and synthesize tumor-targeting antibodies. I am also interested in the mechanisms of cancer metastasis. My research involves the characterization of circulating tumor cells. | I am interested in developing cancer therapeutics using protein engineering, in particular affinity maturation with yeast surface display developed by the Wittrup lab. I design and synthesize tumor-targeting antibodies. I am also interested in the mechanisms of cancer metastasis. My research involves the characterization of circulating tumor cells. | ||
==Previous research experience== | |||
2007-2008 The Institute of Bioengineering and Nanotechnology Singapore | |||
Advisor: Dr. Andrew Wan | |||
Encapsulation of pancreatic islets with polyelectrolyte fibers for immunoisolation | |||
Heterospheroid as 3D tumor model | |||
2005-2007 The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore | |||
Advisor: Dr. Elizabeth Jaffee | |||
• Characterization of Foxp3+ CD8+ tumor infiltrating lymphocytes in FVB and neu-N transgenic mouse models. Functional studies included surface staining, in vitro suppression, in vitro expansion and adoptive transfer. | |||
2006 The Weatherall Institute of Molecular Medicine Oxford University | |||
Advisor: Dr. Vincenzo Cerundolo | |||
• Cloning of CD1e from NKT cells | |||
• Cloning of gamma-delta TCR | |||
2004-2006 The Institute of Molecular Cell Biology Singapore | |||
Revision as of 16:25, 17 January 2010
Graduate Student
Wittrup Lab
Department of Biological Engineering
Massachusetts Institute of Technology
Office: E19-563
Email: xyao@mit.edu
Website
Education
- 2008 - current, PhD, MIT
- 2007, BS, Johns Hopkins
Research interests
I am interested in developing cancer therapeutics using protein engineering, in particular affinity maturation with yeast surface display developed by the Wittrup lab. I design and synthesize tumor-targeting antibodies. I am also interested in the mechanisms of cancer metastasis. My research involves the characterization of circulating tumor cells.
Previous research experience
2007-2008 The Institute of Bioengineering and Nanotechnology Singapore Advisor: Dr. Andrew Wan Encapsulation of pancreatic islets with polyelectrolyte fibers for immunoisolation Heterospheroid as 3D tumor model
2005-2007 The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Advisor: Dr. Elizabeth Jaffee • Characterization of Foxp3+ CD8+ tumor infiltrating lymphocytes in FVB and neu-N transgenic mouse models. Functional studies included surface staining, in vitro suppression, in vitro expansion and adoptive transfer.
2006 The Weatherall Institute of Molecular Medicine Oxford University Advisor: Dr. Vincenzo Cerundolo • Cloning of CD1e from NKT cells • Cloning of gamma-delta TCR
2004-2006 The Institute of Molecular Cell Biology Singapore
