User:Xiaosai Yao: Difference between revisions

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[[Image:XYprofile.png|thumb|left]]
[[Image:XYprofile.png|thumb|left]]


Graduate Student<br>
Graduate Student<br>
Wittrup Lab<br>
[http://web.mit.edu/kdw-lab/ Wittrup Lab] <br>
Department of Biological Engineering<br>
Department of Biological Engineering<br>
Massachusetts Institute of Technology
Massachusetts Institute of Technology<br>
 
 
Office: E19-563 <br>
Email: [[Special:Emailuser/Xiaosai Yao|xyao@mit.edu]]<br>
[http://web.mit.edu/kdw-lab/people/yao.html Website]<br>


==Contact Info==






*Office: E19-563
*Email: [[Special:Emailuser/Xiaosai Yao|xyao@mit.edu]]
*[http://web.mit.edu/kdw-lab/people/yao.html Website]


==Education==
==Education==
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==Research interests==
==Research interests==
<!-- Feel free to add brief descriptions to your research interests as well -->
<!-- Feel free to add brief descriptions to your research interests as well -->
# I am interested in
I am interested in developing cancer therapeutics using protein engineering, in particular affinity maturation with yeast surface display developed by the Wittrup lab. I design and synthesize tumor-targeting antibodies. I am also interested in the mechanisms of cancer metastasis. My research involves the characterization of circulating tumor cells.
 
==Previous research experience==
 
 
*'''Institute of Bioengineering and Nanotechnology''' Singapore, 2007-2008  <br>
Advisor: Dr. Andrew Wan <br>
Encapsulation of pancreatic islets with polyelectrolyte fibers for immunoisolation<br>
 
 
*'''The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins''' Baltimore, 2005-2007 <br>
Advisor: Dr. Elizabeth Jaffee <br>
Characterization of Foxp3+ CD8+ tumor infiltrating lymphocytes in FVB and neu-N transgenic mouse models <br>
 
*'''Weatherall Institute of Molecular Medicine''' Oxford University, 2006 <br>
Advisor: Dr. Vincenzo Cerundolo <br>
Study of CD1e and gamma-delta TCR <br>
 
 
*'''Institute of Molecular Cell Biology''' Singapore, 2004-2006<br>
Advisor: Prof. Wanjin Hong<br>
Characterization of SIMPLE (Small Integral Membrane Protein of Lysosome/Late Endosome)<br>

Latest revision as of 16:34, 17 January 2010




Graduate Student
Wittrup Lab
Department of Biological Engineering
Massachusetts Institute of Technology


Office: E19-563
Email: xyao@mit.edu
Website



Education

  • 2008 - current, PhD, MIT
  • 2007, BS, Johns Hopkins

Research interests

I am interested in developing cancer therapeutics using protein engineering, in particular affinity maturation with yeast surface display developed by the Wittrup lab. I design and synthesize tumor-targeting antibodies. I am also interested in the mechanisms of cancer metastasis. My research involves the characterization of circulating tumor cells.

Previous research experience

  • Institute of Bioengineering and Nanotechnology Singapore, 2007-2008

Advisor: Dr. Andrew Wan
Encapsulation of pancreatic islets with polyelectrolyte fibers for immunoisolation


  • The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, 2005-2007

Advisor: Dr. Elizabeth Jaffee
Characterization of Foxp3+ CD8+ tumor infiltrating lymphocytes in FVB and neu-N transgenic mouse models


  • Weatherall Institute of Molecular Medicine Oxford University, 2006

Advisor: Dr. Vincenzo Cerundolo
Study of CD1e and gamma-delta TCR


  • Institute of Molecular Cell Biology Singapore, 2004-2006

Advisor: Prof. Wanjin Hong
Characterization of SIMPLE (Small Integral Membrane Protein of Lysosome/Late Endosome)