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Graduate Student<br> | |||
[http://web.mit.edu/kdw-lab/ Wittrup Lab] <br> | |||
Department of Biological Engineering<br> | |||
Massachusetts Institute of Technology<br> | |||
Office: E19-563 <br> | |||
Email: [[Special:Emailuser/Xiaosai Yao|xyao@mit.edu]]<br> | |||
[http://web.mit.edu/kdw-lab/people/yao.html Website]<br> | |||
==Education== | ==Education== | ||
<!--Include info about your educational background--> | <!--Include info about your educational background--> | ||
* 2008-current, PhD, MIT | * 2008 - current, PhD, MIT | ||
* 2007, BS, Johns Hopkins | * 2007, BS, Johns Hopkins | ||
==Research interests== | ==Research interests== | ||
<!-- Feel free to add brief descriptions to your research interests as well --> | <!-- Feel free to add brief descriptions to your research interests as well --> | ||
I am interested in developing cancer therapeutics using protein engineering, in particular affinity maturation with yeast surface display developed by the Wittrup lab. I design and synthesize tumor-targeting antibodies. I am also interested in the mechanisms of cancer metastasis. My research involves the characterization of circulating tumor cells. | |||
==Previous research experience== | |||
*'''Institute of Bioengineering and Nanotechnology''' Singapore, 2007-2008 <br> | |||
Advisor: Dr. Andrew Wan <br> | |||
Encapsulation of pancreatic islets with polyelectrolyte fibers for immunoisolation<br> | |||
*'''The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins''' Baltimore, 2005-2007 <br> | |||
Advisor: Dr. Elizabeth Jaffee <br> | |||
Characterization of Foxp3+ CD8+ tumor infiltrating lymphocytes in FVB and neu-N transgenic mouse models <br> | |||
*'''Weatherall Institute of Molecular Medicine''' Oxford University, 2006 <br> | |||
Advisor: Dr. Vincenzo Cerundolo <br> | |||
Study of CD1e and gamma-delta TCR <br> | |||
*'''Institute of Molecular Cell Biology''' Singapore, 2004-2006<br> | |||
Advisor: Prof. Wanjin Hong<br> | |||
Characterization of SIMPLE (Small Integral Membrane Protein of Lysosome/Late Endosome)<br> | |||
Latest revision as of 16:34, 17 January 2010
Graduate Student
Wittrup Lab
Department of Biological Engineering
Massachusetts Institute of Technology
Office: E19-563
Email: xyao@mit.edu
Website
Education
- 2008 - current, PhD, MIT
- 2007, BS, Johns Hopkins
Research interests
I am interested in developing cancer therapeutics using protein engineering, in particular affinity maturation with yeast surface display developed by the Wittrup lab. I design and synthesize tumor-targeting antibodies. I am also interested in the mechanisms of cancer metastasis. My research involves the characterization of circulating tumor cells.
Previous research experience
- Institute of Bioengineering and Nanotechnology Singapore, 2007-2008
Advisor: Dr. Andrew Wan
Encapsulation of pancreatic islets with polyelectrolyte fibers for immunoisolation
- The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, 2005-2007
Advisor: Dr. Elizabeth Jaffee
Characterization of Foxp3+ CD8+ tumor infiltrating lymphocytes in FVB and neu-N transgenic mouse models
- Weatherall Institute of Molecular Medicine Oxford University, 2006
Advisor: Dr. Vincenzo Cerundolo
Study of CD1e and gamma-delta TCR
- Institute of Molecular Cell Biology Singapore, 2004-2006
Advisor: Prof. Wanjin Hong
Characterization of SIMPLE (Small Integral Membrane Protein of Lysosome/Late Endosome)
