User:Tsbayer

Travis Bayer

I work on synthetic biology in the Smolke Lab at Caltech. I used to work for the Ellington Lab doing directed evolution.

Interests

• Robustness and evolvability in biology
• Engineering life with functional nucleic acids

Publications

• Tabor JJ, Bayer TS, Simpson ZB , Levy M, Ellington AD. Operons are genetic noise insulators. Submitted. 2006.

• Bayer TS, Smolke CD. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nature Biotechnology. 2005 Mar;23(3):337-43.

• Bayer TS, Booth LN, Knudsen SM, Ellington AD. Arginine-rich motifs present multiple interfaces for specific binding by RNA. RNA. 2005 Dec;11(12):1848-57.

• Kirby R, Cho EJ, Gehrke B, Bayer T, Park YS, Neikirk DP, McDevitt JT, Ellington AD. Aptamer-based sensor arrays for the detection and quantitation of proteins. Analytical Chemistry. 2004 Jul 15;76(14):4066-75.

• Cox JC, Hayhurst A, Hesselberth J, Bayer TS, Georgiou G, Ellington AD. Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer. Nucleic Acids Research. 2002 Oct 15;30(20):e108.

• Cox JC, Rajendran M, Riedel T, Davidson EA, Sooter LJ, Bayer TS, Schmitz-Brown M, Ellington AD. Automated acquisition of aptamer sequences. Combinatorial Chemistry and High Throughput Screening. 2002 Jun;5(4):289-99.

Bi23: Nucleic acids from origins to bioengineering

Last term I got to teach a class that I made up. It was mostly about synthetic biology, although I tried to talk about origins some. Then it devolved into a discussion of coming up with clever 'biohacks', or ways to reprogram functions of natural and synthetic genetic systems. Mostly for devious ends. I'll put up the slides and notes for it, and some of our hacks...