User:Thomas Crouzier: Difference between revisions
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Revision as of 09:58, 6 February 2013
I am a new member of OpenWetWare!
Contact Info
- Thomas Crouzier
- MIT
- Find me in building 56, room 367
- Email : crouzier at mit dot edu
Education
- 01/2006 – 03/2010
PhD student at the University of Montpellier (France) working on surface modification of biomaterials. Under the supervision of Pr. C. Picart. I engineered a new type of bioactive surface modification made from biocompatible polymer loaded with a growth factor. The delivery of the protein triggers the formation of bone in contact with the material. A collaboration in association with orthopedic surgeons has been established for further development.
08/2005- 01/2006 Masters in bioengineering as part of a double degree exchange program with the University of Oklahoma (USA). Under the supervision of Pr. P. McFetridge. I developed of a scaffold material for peripheral nerve and cardiovascular tissue engineering. The research gave rise to two peered reviewed articles and a Masters degree in Biological Engineering.
09/2003- 01/2006 Bioengineering student (Institute of Engineering Sciences - University of Clermont-Ferrand, France).
Research interests
Hi Everybody. I'm a postdoc in Katharina Ribbeck's lab. The lab is multidisciplinary and focused on biological hydrogels and in particular mucus and biofilms. My work is focused on the study of cell-mucin interactions, the physicochemical characterization of mucin coatings and the development of mucin-based biomaterials. I have been extracting the essential component of mucus (mucins), and am doing exploratory work to expose the potential of this molecule to be used as a building block for new biomaterials. These biomaterials can be used to better understand mucus (its biophysical properties and its biology) and for biomedical applications such as drug delivery.
- Biomaterials
- cell-material interactions
- Biopolymers and biomacromolecules
Selected Publications
- Crouzier T, Beckwitt CH, and Ribbeck K. Mucin multilayers assembled through sugar-lectin interactions. Biomacromolecules. 2012 Oct 8;13(10):3401-8. DOI:10.1021/bm301222f |
- Crouzier T, Sailhan F, Becquart P, Guillot R, Logeart-Avramoglou D, and Picart C. The performance of BMP-2 loaded TCP/HAP porous ceramics with a polyelectrolyte multilayer film coating. Biomaterials. 2011 Oct;32(30):7543-54. DOI:10.1016/j.biomaterials.2011.06.062 |
- Crouzier T, Fourel L, Boudou T, Albigès-Rizo C, and Picart C. Presentation of BMP-2 from a soft biopolymeric film unveils its activity on cell adhesion and migration. Adv Mater. 2011 Mar 25;23(12):H111-8. DOI:10.1002/adma.201004637 |
- Boudou T, Crouzier T, Nicolas C, Ren K, and Picart C. Polyelectrolyte multilayer nanofilms used as thin materials for cell mechano-sensitivity studies. Macromol Biosci. 2011 Jan 10;11(1):77-89. DOI:10.1002/mabi.201000301 |
- Boudou T, Crouzier T, Auzély-Velty R, Glinel K, and Picart C. Internal composition versus the mechanical properties of polyelectrolyte multilayer films: the influence of chemical cross-linking. Langmuir. 2009 Dec 15;25(24):13809-19. DOI:10.1021/la9018663 |
- Boudou T, Crouzier T, Ren K, Blin G, and Picart C. Multiple functionalities of polyelectrolyte multilayer films: new biomedical applications. Adv Mater. 2010 Jan 26;22(4):441-67. DOI:10.1002/adma.200901327 |
- Crouzier T, Szarpak A, Boudou T, Auzély-Velty R, and Picart C. Polysaccharide-blend multilayers containing hyaluronan and heparin as a delivery system for rhBMP-2. Small. 2010 Mar 8;6(5):651-62. DOI:10.1002/smll.200901728 |
- Crouzier T, Ren K, Nicolas C, Roy C, and Picart C. Layer-by-layer films as a biomimetic reservoir for rhBMP-2 delivery: controlled differentiation of myoblasts to osteoblasts. Small. 2009 Mar;5(5):598-608. DOI:10.1002/smll.200800804 |
- Crouzier T and Picart C. Ion pairing and hydration in polyelectrolyte multilayer films containing polysaccharides. Biomacromolecules. 2009 Feb 9;10(2):433-42. DOI:10.1021/bm8012378 |
- Crouzier T, Nimmagadda A, Nollert MU, and McFetridge PS. Modification of single walled carbon nanotube surface chemistry to improve aqueous solubility and enhance cellular interactions. Langmuir. 2008 Nov 18;24(22):13173-81. DOI:10.1021/la801999n |
- Ren K, Crouzier T, Roy C, and Picart C. Polyelectrolyte multilayer films of controlled stiffness modulate myoblast cells differentiation. Adv Funct Mater. 2008;18(9):1378-1389. DOI:10.1002/adfm.200701297 |
- Crouzier T, McClendon T, Tosun Z, and McFetridge PS. Inverted human umbilical arteries with tunable wall thicknesses for nerve regeneration. J Biomed Mater Res A. 2009 Jun;89(3):818-28. DOI:10.1002/jbm.a.32103 |