User:Sunny Sharma

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*[[Special:Emailuser/Sunny Sharma|Email me through OpenWetWare]]
*[[Special:Emailuser/Sunny Sharma|Email me through OpenWetWare]]
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I am graduate student in [[Entian´s Lab]] at Goethe University, Frankfurt am Main.
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Research Associate at Goethe University, Frankfurt am Main.
==Education==
==Education==
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<!--Include info about your educational background-->
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* PhD student at Institute of Molecular Biosciences, Goethe University, Frankfurt am Main, Germany [http://www.uni-frankfurt.de/fb/fb15/english/institute/inst-3-mol-biowiss/]
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* Research Associate at Institute of Molecular Biosciences, Goethe University, Frankfurt am Main, Germany [http://www.uni-frankfurt.de/fb/fb15/english/institute/inst-3-mol-biowiss/]
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* 2014, PhD (Biology), Goethe University, Frankfurt am Main, Germany [http://www.uni-frankfurt.de/fb/fb15/english/institute/inst-3-mol-biowiss/]
* 2007, MS (Molecular Biology & Biochemistry), Guru Nanak Dev University, Amritsar, India [http://department.gndu.ac.in/department/molecular.asp]
* 2007, MS (Molecular Biology & Biochemistry), Guru Nanak Dev University, Amritsar, India [http://department.gndu.ac.in/department/molecular.asp]
*2005, BS, Bangalore University, Bangalore, India [http://www.bangaloreuniversity.ac.in/]
*2005, BS, Bangalore University, Bangalore, India [http://www.bangaloreuniversity.ac.in/]
== Awards ==
== Awards ==
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EMBO (European Molecular Biology Organisation) Long Term Fellowship. (2014-2016)[http://www.embo.org/]
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DAAD (Deutsche Akademische Austauschdienst) PhD scholarship (2010 - 2013) [https://www.daad.de/de/index.html]
DAAD (Deutsche Akademische Austauschdienst) PhD scholarship (2010 - 2013) [https://www.daad.de/de/index.html]
CEF (Excellence Cluster-Frankfurt am Main) PhD fellowship (2009 - 2010) [http://www.cef-mc.de/index.php?id=2]
CEF (Excellence Cluster-Frankfurt am Main) PhD fellowship (2009 - 2010) [http://www.cef-mc.de/index.php?id=2]
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ICMR (Indian Council of Medical Research) Junior Research Fellowship (2009 - 2010) [http://www.cef-mc.de/index.php?id=2]
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ICMR (Indian Council of Medical Research) Junior Research Fellowship (2009 - 2010) [http://www.icmr.nic.in/]
==Research interests==
==Research interests==
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# Ribosome Biogenesis
# Ribosome Biogenesis
# RNA modifications
# RNA modifications
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# Developmental Biology
#Immunology
#Immunology
# Gerontology
# Gerontology
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==Publications==
==Publications==
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<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed -->
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1)‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification.[http://www.cell.com/trends/biochemical-sciences/abstract/S0968-0004%2815%2900139-5]
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<biblio>
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# Paper1 pmid=23558746
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# Paper2 pmid=23180764  
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2) The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent.[http://nar.oxfordjournals.org/content/early/2015/09/13/nar.gkv895.full]
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#Paper3 pmid=20819262
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3) Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1.[http://nar.oxfordjournals.org/content/early/2015/02/03/nar.gkv075.full]
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4) Identification of a new ribose methylation in the 18S rRNA of S. cerevisiae.[http://nar.oxfordjournals.org/content/early/2015/02/03/nar.gkv058.abstract]
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5) Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.[http://www.ncbi.nlm.nih.gov/pubmed/25635753]
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6) Absolute and relative quantification of RNA modifications via biosynthetic isotopomers.[http://www.ncbi.nlm.nih.gov/pubmed/25129236]
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7) Partial methylation at Am100 in 18S rRNA of baker´s yeast shows ribosome heterogeneity on the level of eukaryotic rRNA modification. Plos One [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0089640]
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8) Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.[http://nar.oxfordjournals.org/content/early/2013/12/11/nar.gkt1281.full]
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9) Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.[http://www.ncbi.nlm.nih.gov/pubmed/23913415]
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10) Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae.[http://www.ncbi.nlm.nih.gov/pubmed/23558746]
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11) Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.[http://www.ncbi.nlm.nih.gov/pubmed/23180764]
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12) Association of P2X7 receptor +1513 (A-->C) polymorphism with tuberculosis in a Punjabi population.[http://www.ncbi.nlm.nih.gov/pubmed/20819262]
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==Conferences/ Workshops==
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# Plenary talk at 10th Ribosome Synthesis meeting 19th-25th August, Brussels.[http://events.embo.org/15-ribosomes/]
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# Seminar at RNA club, 16th October 2013 [http://www.rnaclub.de/img/RNACLUB_20131016.pdf ]
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# Plenary talk at Yeast Meeting, Frankfurt 2013 [http://www.yeast-2013.org/faces/index]
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# Poster presentation at 18th Annual RNA meeting of the RNA society, Davos, Switzerland [http://www.rnasociety.org/conferences/rna-2013/]
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# Seminar at RNA club, 26th September 2012 [http://www.rnaclub.de/img/RNACLUB_20120926.pdf]
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# Poster presentation at 9th International Conference on Ribosome Synthesis, Banff, Canada [http://www.rochester.edu/College/BIO/ribosyn2012/]
==Useful links==
==Useful links==
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*http://www.muk.uni-frankfurt.de/53895688/033?
*http://www.yeastgenome.org/
*http://www.yeastgenome.org/
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*http://www.rnaclub.de
*http://people.biochem.umass.edu/fournierlab/3dmodmap/main.php
*http://people.biochem.umass.edu/fournierlab/3dmodmap/main.php
*http://modomics.genesilico.pl/
*http://modomics.genesilico.pl/

Current revision

Contents

Contact Info

  • Sunny Sharma
  • Institute of Molecular Biosciences, Max-von-Laue Strasse-9, Campus Riedberg, Goethe University
  • Frankfurt am Main, Hesse, Germany.
  • Email me through OpenWetWare

Research Associate at Goethe University, Frankfurt am Main.

Education

  • Research Associate at Institute of Molecular Biosciences, Goethe University, Frankfurt am Main, Germany [1]
  • 2014, PhD (Biology), Goethe University, Frankfurt am Main, Germany [2]
  • 2007, MS (Molecular Biology & Biochemistry), Guru Nanak Dev University, Amritsar, India [3]
  • 2005, BS, Bangalore University, Bangalore, India [4]

Awards

EMBO (European Molecular Biology Organisation) Long Term Fellowship. (2014-2016)[5]

DAAD (Deutsche Akademische Austauschdienst) PhD scholarship (2010 - 2013) [6]

CEF (Excellence Cluster-Frankfurt am Main) PhD fellowship (2009 - 2010) [7]

ICMR (Indian Council of Medical Research) Junior Research Fellowship (2009 - 2010) [8]

Research interests

  1. Ribosome Biogenesis
  2. RNA modifications
  3. Developmental Biology
  4. Immunology
  5. Gerontology

Publications

1)‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification.[9]


2) The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent.[10]


3) Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1.[11]


4) Identification of a new ribose methylation in the 18S rRNA of S. cerevisiae.[12]


5) Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.[13]


6) Absolute and relative quantification of RNA modifications via biosynthetic isotopomers.[14]


7) Partial methylation at Am100 in 18S rRNA of baker´s yeast shows ribosome heterogeneity on the level of eukaryotic rRNA modification. Plos One [15]


8) Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.[16]


9) Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.[17]


10) Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae.[18]


11) Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.[19]


12) Association of P2X7 receptor +1513 (A-->C) polymorphism with tuberculosis in a Punjabi population.[20]

Conferences/ Workshops

  1. Plenary talk at 10th Ribosome Synthesis meeting 19th-25th August, Brussels.[21]
  2. Seminar at RNA club, 16th October 2013 [22]
  3. Plenary talk at Yeast Meeting, Frankfurt 2013 [23]
  4. Poster presentation at 18th Annual RNA meeting of the RNA society, Davos, Switzerland [24]
  5. Seminar at RNA club, 26th September 2012 [25]
  6. Poster presentation at 9th International Conference on Ribosome Synthesis, Banff, Canada [26]

Useful links

Personal tools