User:Stuart S. Levine

Contact Info

Stuart S. Levine (an artistic interpretation)

• Stuart S. Levine
• BioMicro Center
• Massachusetts Institute of Technology, 68-304d
• 77 Massachusetts Ave., Cambridge, MA 02142
• Email me through OpenWetWare

I am the Director of the BioMicro Center at MIT.

Education

• 2004, PhD, Harvard University
• 1997, BS, MIT

Research interests

1. Interest 1
2. Interest 2
3. Interest 3

Publications

1. Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, Hannett N, Sharp PA, Bartel DP, Jaenisch R, and Young RA. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell. 2008 Aug 8;134(3):521-33. DOI:10.1016/j.cell.2008.07.020 |
2. Creyghton MP, Markoulaki S, Levine SS, Hanna J, Lodato MA, Sha K, Young RA, Jaenisch R, and Boyer LA. H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment. Cell. 2008 Nov 14;135(4):649-61. DOI:10.1016/j.cell.2008.09.056 |
3. Guenther MG, Levine SS, Boyer LA, Jaenisch R, and Young RA. A chromatin landmark and transcription initiation at most promoters in human cells. Cell. 2007 Jul 13;130(1):77-88. DOI:10.1016/j.cell.2007.05.042 |
4. Marson A, Kretschmer K, Frampton GM, Jacobsen ES, Polansky JK, MacIsaac KD, Levine SS, Fraenkel E, von Boehmer H, and Young RA. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature. 2007 Feb 22;445(7130):931-5. DOI:10.1038/nature05478 |
5. Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, Yuan B, Bell GW, Herbolsheimer E, Hannett NM, Sun K, Odom DT, Otte AP, Volkert TL, Bartel DP, Melton DA, Gifford DK, Jaenisch R, and Young RA. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 2006 Apr 21;125(2):301-13. DOI:10.1016/j.cell.2006.02.043 |
6. Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, and Jaenisch R. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 2006 May 18;441(7091):349-53. DOI:10.1038/nature04733 |
7. Kiburz BM, Reynolds DB, Megee PC, Marston AL, Lee BH, Lee TI, Levine SS, Young RA, and Amon A. The core centromere and Sgo1 establish a 50-kb cohesin-protected domain around centromeres during meiosis I. Genes Dev. 2005 Dec 15;19(24):3017-30. DOI:10.1101/gad.1373005 |
8. Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, and Young RA. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 2005 Sep 23;122(6):947-56. DOI:10.1016/j.cell.2005.08.020 |
9. Pokholok DK, Harbison CT, Levine S, Cole M, Hannett NM, Lee TI, Bell GW, Walker K, Rolfe PA, Herbolsheimer E, Zeitlinger J, Lewitter F, Gifford DK, and Young RA. Genome-wide map of nucleosome acetylation and methylation in yeast. Cell. 2005 Aug 26;122(4):517-27. DOI:10.1016/j.cell.2005.06.026 |
10. Levine SS, King IF, and Kingston RE. Division of labor in polycomb group repression. Trends Biochem Sci. 2004 Sep;29(9):478-85. DOI:10.1016/j.tibs.2004.07.007 |
11. Hughes CM, Rozenblatt-Rosen O, Milne TA, Copeland TD, Levine SS, Lee JC, Hayes DN, Shanmugam KS, Bhattacharjee A, Biondi CA, Kay GF, Hayward NK, Hess JL, and Meyerson M. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Mol Cell. 2004 Feb 27;13(4):587-97. DOI:10.1016/s1097-2765(04)00081-4 |
12. Levine SS, Weiss A, Erdjument-Bromage H, Shao Z, Tempst P, and Kingston RE. The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol Cell Biol. 2002 Sep;22(17):6070-8. DOI:10.1128/MCB.22.17.6070-6078.2002 |

Useful links

• Introductory tutorial
• OpenWetWare help pages