User:Steven J. Koch/MTC/April 19 2011: Difference between revisions
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* Assignment due Tuesday April 26 | * Assignment due Tuesday April 26 | ||
* What is going on in gliding assay? | * [[/GMA|What is going on in gliding assay?]] | ||
** Andy video dissertation | ** Andy video dissertation: http://openwetware.org/wiki/User:Andy_Maloney/Kinesin_%26_Microtubule_Page | ||
** Kinesin modeling (mostly Larry) | ** Kinesin modeling (mostly Larry) | ||
*** Neck linker docking | *** Neck linker docking | ||
Revision as of 05:48, 19 April 2011
Tuesday April 19, 2011. Microtubule gliding assay / kinesin modeling
- Apology for being sick / missing so much. Reiterate the goals of the class
- Learn some molecular biophysics
- More importantly: learn resources for doing molecular biophysics research (PDB, OpenWetWare, S30, Mendeley, Figshare, etc.)
- Review of field trip -- watch movies!
- Assignment due Tuesday April 26
- What is going on in gliding assay?
- Andy video dissertation: http://openwetware.org/wiki/User:Andy_Maloney/Kinesin_%26_Microtubule_Page
- Kinesin modeling (mostly Larry)
- Neck linker docking
- What is best way to model tension in the neck linker (chain of amino acids)
- GROUP WORK: In the two-headed bound state, does neck-linker docking INCREASE or DECREASE or KEEP SAME the tension
- (A) Back head docks; (B) Front head docks
- Discuss with partner and make answers for (A) and (B)
- Neck linker docking
