User:Sean C. Sleight

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*[[Special:Emailuser/Sean C. Sleight|Email me through OpenWetWare]]
*[[Special:Emailuser/Sean C. Sleight|Email me through OpenWetWare]]
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I'm a postdoc in Herbert Sauro's lab at University of Washington.  I have just started a synthetic biology project and will be an advisor for the UW iGEM 2008 team.  Hopefully I will be able to contribute something here soon.
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I'm a postdoc in Herbert Sauro's lab at University of Washington.  I am working on a synthetic biology project and am an advisor for the UW iGEM team.
==Education==
==Education==
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==Research interests==
==Research interests==
<!-- Feel free to add brief descriptions to your research interests as well -->
<!-- Feel free to add brief descriptions to your research interests as well -->
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# Synthetic biology (standards, modular gene networks, stochasticity, feed-forward loops)
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# Synthetic biology
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# Evolution (using it as a friend of synthetic biology instead of an enemy)
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# Experimental and directed evolution
# Mutation rates under stress
# Mutation rates under stress
==Publications==
==Publications==
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*Sleight S.C., N.S. Wigginton, and R.E. Lenski.
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*Sleight S.C., C. Orlic, D. Schneider, and R.E. Lenski
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Increased susceptibility to repeated freeze-thaw cycles in Escherichia coli following long-term evolution in a benign environment. 2006. BMC Evolutionary Biology 6: 104 [8 pp].
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Genetic basis of evolutionary adaptation by Escherichia coli to stressful cycles of freezing, thawing and growth. 2008. Genetics Sep;180(1):431-43.
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*Sleight S.C. and R.E. Lenski.
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*Sleight S.C. and R.E. Lenski
Evolutionary adaptation to freeze-thaw-growth cycles in Escherichia coli. 2007. Physiological and Biochemical Zoology 80(4): 370-385.
Evolutionary adaptation to freeze-thaw-growth cycles in Escherichia coli. 2007. Physiological and Biochemical Zoology 80(4): 370-385.
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*Sleight S.C., C. Orlic, D. Schneider, and R.E. Lenski.
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*Sleight S.C., N.S. Wigginton, and R.E. Lenski
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Genetic basis of evolutionary adaptation by Escherichia coli to stressful cycles of freezing, thawing and growth (submitted to Genetics).
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Increased susceptibility to repeated freeze-thaw cycles in Escherichia coli following long-term evolution in a benign environment. 2006. BMC Evolutionary Biology 6: 104 [8 pp].
==Useful links==
==Useful links==
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*[http://openwetware.org/wiki/In-fusion_biobrick_assembly In-Fusion BioBrick Assembly]
*[[OpenWetWare:Welcome|Introductory tutorial]]
*[[OpenWetWare:Welcome|Introductory tutorial]]
*[[Help|OpenWetWare help pages]]
*[[Help|OpenWetWare help pages]]

Current revision

Contents

Contact Info

Sean C. Sleight (an artistic interpretation)
Sean C. Sleight (an artistic interpretation)

I'm a postdoc in Herbert Sauro's lab at University of Washington. I am working on a synthetic biology project and am an advisor for the UW iGEM team.

Education

  • 2007, PhD, Michigan State University, Microbiology and Molecular Genetics
  • 1999, BS, University of Arizona, Molecular and Cellular Biology

Research interests

  1. Synthetic biology
  2. Experimental and directed evolution
  3. Mutation rates under stress

Publications

  • Sleight S.C., C. Orlic, D. Schneider, and R.E. Lenski

Genetic basis of evolutionary adaptation by Escherichia coli to stressful cycles of freezing, thawing and growth. 2008. Genetics Sep;180(1):431-43.

  • Sleight S.C. and R.E. Lenski

Evolutionary adaptation to freeze-thaw-growth cycles in Escherichia coli. 2007. Physiological and Biochemical Zoology 80(4): 370-385.

  • Sleight S.C., N.S. Wigginton, and R.E. Lenski

Increased susceptibility to repeated freeze-thaw cycles in Escherichia coli following long-term evolution in a benign environment. 2006. BMC Evolutionary Biology 6: 104 [8 pp].

Useful links

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