User:S. Saini
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Research interests
- Network Dynamics
- Statistics and Dynamics of Evolution in Microbial Populations
- Bacterial Pathogenesis
Openings
- PhD Positions. Interested students are requested to write to Supreet with their CV.
- Post-doctoral researchers interested in theoretical & computational biology are requested to contact Supreet with their CV and research proposal.
Research Group
Principal Investigator
- Supreet Saini (Assistant Professor) | PhD & MS (University of Illinois, Urbana-Champaign) | B.Tech. (IIT Delhi) | saini AT che.iitb.ac.in
Graduate Students (for PhD)
- Kirti Jain (2011 - date) | MSc. (Life Science) NIT Rourkela | kirtijn1 AT gmail.com
- Debika Choudhury (2011 - date) | MSc. (Microbiology) University of Calcutta | debika217 AT gmail.com
- Dinaker Vudhva (2014 - date) | MSc (Life Science) Jawaharlal Nehru University | dinakar.wadhwa AT gmail.com
- R G Brajesh (2015 - date) | MTech (Biotechnology) Anna University | brajeshrg AT gmail.com
- Dibyendu Dutta (2016 - date) | MSc & BSc (Systems Biology) Hyderabad University | debudutta1 AT gmail.com
Graduate Students (for Masters)
- Nikhil Raj (2015 - date)
- Rohit Garg (2015 - date)
Undergraduates
Project Research Fellows
- Balaji Kumar (2015 - date)
Visiting Students
- Isha Shroff (DY Patil, Navi Mumbai) (2016 - date)
Past Members
Graduate Students (for PhD)
- Manish Kumar (2011 - 2015) [Post Doc, Jens Nielsen's group, manish1.biotech AT gmail.com]
Graduate Students (for Masters)
- Nitesh Meena (2013 - 2015)
- Ashish (2012 - 2014) [Co-Founder, The Zero Games Pvt. Ltd, ashish.19766 AT gmail.com]
- Gauri Shankar Choudhury (2012 - 2014)
Project Research Staff
- Divyae Prasad (2014)
Undergraduates
- [2014] Piyush Lakhmani, Amit Aggarwal
- [2013] Chaitanya Gupta, Amit Pradhan
Visiting Students
- [2014] Sumedha Mangal (IIT BHU), Vaibhav Pathak (IIT BHU), Balaji Kumar (IIT Madras), Shriyam (Banasthali University)
Publications
- Analysis of optimality of the standard genetic code. bioRxiv (2015)
- Control of marRAB operon in Escherichia coli via autoactivation and autorepression. Biophysical Journal (2015)
- Revisiting Demand Rules for Gene Regulation. Molecular BioSystems, bioRxiv (2015)
- Mathematical model of flagella gene expression dynamics in Salmonella enterica serovar typhimurium. Systems and Synthetic Biology (2015)
- Elementary mode analysis reveals that Clostridium acetobutylicum modulates its metabolic strategy under external stress. Molecular BioSystems (2014)
- Acetone-butanol-ethanol fermentation analysis using only high performance liquid chromatography. Analytical Methods (2014)
- Characterization of Performance and Dynamics of Genetic Networks. IFAC Computer Applications in Biotechnology (2013)
- Role of feedback and network architecture in controlling virulence gene expression in Bordetella. Molecular BioSystems (2013)
- Role of extracellular cues to trigger the metabolic phase shifting from acidogenesis to solventogenesis in Clostridium acetobutylicum. Bioresource Technology (2013)
- Academic Ethics at the Undergraduate Level: Case Study from the Formative Years of the Institute. Journal of Academic Ethics (2013)
- Interplay between Fur and HNS in controlling virulence gene expression in Salmonella typhimurium. Computers in Biology and Medicine (2012)
- Continuous control of flagellar gene expression by the σ28-FlgM regulatory circuit in Salmonella enterica. Molecular Microbiology (2011)
- The interaction dynamics of a negative feedback loop regulates flagellar number in Salmonella enterica serovar Typhimurium. Molecular Microbiology (2010)
- FliZ induces a kinetic switch in flagellar gene expression. Journal of Bacteriology (2010)
- Role of cross talk in regulating the dynamic expression of the flagellar Salmonella pathogenicity island 1 and type 1 fimbrial genes. Journal of Bacteriology (2010)
- The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella. PLoS Pathogens (2010)
- SprB is the molecular link between Salmonella pathogenicity island 1 (SPI1) and SPI4. Journal of Bacteriology (2010)
- Role of FimW, FimY, and FimZ in regulating the expression of type i fimbriae in Salmonella enterica serovar Typhimurium. Journal of Bacteriology (2009)
- Role of feedback loops in dictating flagellar gene regulation dynamics in Salmonella typhimurium. FOSBE Proceedings IET Systems Biology (2009)
- The rate of protein secretion dictates the temporal dynamics of flagellar gene expression. Molecular Microbiology (2008)
- FliZ Is a posttranslational activator of FlhD4C2-dependent flagellar gene expression. Journal of Bacteriology (2008)
- Pressure drop and heat transfer study in tube-in-tube helical heat exchanger. Chemical Engineering Science (2006)
Conference Presentations/Invited Talks
- Quorum sensing and bacterial strategies. NNMCB Meeting , IISER, Pune (2015)
- Control of mar-sox-rob regulon in E. coli and Salmonella. Bacterial Expressions II , NCBS, Bangalore (2015)
- Does genetic robstness aid adaptability in rapidly evolving microbial populations? Evolutionary Biology Meeting, Marseille, France (2015)
- Crosstalk between arabinose and xylose utilization systems in E. coli. ASM General Meeting, US (2015)
- Control of Mar, Sox, Rob regulon in E. coli. ASM General Meeting, US (2015)
- Evolvability vs. Robustness in rapidly evolving microbial populations. Society of Biological Chemists (India) Annual Meeting, Bhubaneswar (2014)
- Transcriptional interference as a mechanism to control gene expression. IMSc, Chennai (2014)
- Revisiting Demand Rules for Gene Regulation. Center for Excellence in Basic Sciences, Mumbai (2014)
- Characterizing Clostridium acetobutylicum metabolism using constraint-based modeling approach under stress. Clostridium XIII, China (2014)
- Revisiting Demand Rules for Gene Regulation. FEBS-EMBO Meeting, Paris (2014)
- Dynamic regulation of Pathogenicity Islands and Multiple Antibiotic Resistance loci in Salmonella typhimurium. FEBS-EMBO Meeting, Paris (2014)
- Logic of Interacting Quorum Sensing Systems in Bacteria. q-Bio, Santa Fe (2014)
- Introduction to Computational and Systems Biology. Workshop on Bioinformatics Applications and Interdisciplinary Technologies, Haffkine Institute, Mumbai (2014)
- Counting and control in bacteria via Secretion. Bacterial Expressions, NCBS (Bangalore) (2013)
- Impact of network map and architecture on gene expression dynamics. Foundations of Systems Biology in Engineering (FOSBE), Tsuruoka (Japan) (2012)
- Dynamics and Control of the Clostridium acetobutylicum metabolic network. Clostridium XII, Nottingham (United Kingdom) (2012)
Contact
- Supreet Saini, Room 136, Assistant Professor, Chemical Engineering, IIT Bombay, Mumbai - 400 076 | Email: saini AT che.iitb.ac.in
- BioSystems Laboratory, Department of Chemical Engineering, IIT Bombay, Mumbai - 400 076 | Phone: 91 22 2576 4286