User:Nikolai Eroshenko
Research
I am interested in developing techniques for massively parallel analyses of DNA-binding proteins and using such methods to study the principles that govern the evolution of transcription factors. I am also interested in designing enzymes capable of efficient and accurate gene delivery.
Publications
6. Nikolai Eroshenko, George Church (in press) Mutants of Cre recombinase with improved accuracy. Nat Commun
5. Nikolai Eroshenko*, Rukmani Ramachandran*, Vamsi Yadavalli, Raj R. Rao (2013) Effect of substrate stiffness on early human embryonic stem cell differentiation. J Biol Eng 7:7
4. Shilpa Iyer, Ena Xiao, Khaled Alsayegh, Nikolai Eroshenko, Marion J. Riggs, James P. Bennett. Jr & Raj R. Rao (2012) Mitochondrial gene replacement in human pluripotent stem cell derived neural progenitors. Gene Ther 19:469
3. Nikolai Eroshenko*, Sriram Kosuri*, Adam H. Marblestone, Nicholas Conway, George Church (2012) Gene assembly from chip-synthesized oligonucleotides. Curr Prot Chem Biol 4:1
2. Sriram Kosuri*, Nikolai Eroshenko*, Emily LeProust, Michael Super, Jeffrey Way, Jin Billy Li & George Church (2010) Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips. Nat Biotechnol 28:1295
1. Sheena Abraham, Nikolai Eroshenko & Raj R. Rao (2009) Role of bioinspired polymers in determination of pluripotent stem cell fate. Regen Med 4:561
Patents
1. George Church, Sriram Kosuri, Nikolai Eroshenko (pending) Orthogonal amplification and assembly of nucleic acid sequences US Patent App 2011057075 (Harvard)
Labs
George Church (2009-now)
Wyss Institute (2009-2011)
Raj Rao (2006-2008)
Curtis Taylor (2006-2007)
Education
Harvard University (2008-now) PhD candidate, Bioengineering
Virginia Commonwealth University (2005-2008) BS, Biomedical Engineering
Contact
eroshenkona AT gmail
Nikolai Eroshenko
77 Ave. Louis Pasteur
NRB 238
Boston, MA 02115