User:Msoh

M13 Reengineering

Gene	Ideas
I	influence how it assembles and interacts with IV to alter size/properties of channels, this could be important if the size or shape of the phage is changed
II	make it sensitive to a mechanism that can control the proliferation of the phage, perhaps make it require a cofactor that must be added before replication begins
III	present larger molecules (including myc epitope), change its interactions with bacterial surface molecules to influence which phages are able to replicate, change which bacteria the phage is able to interact with
IV	influence its assembly and interaction with I/XI to alter size/properties of channels
V	make it sensitive to mechanism that allows for assay of DNA amount and location, change its assembly mechanism to influence phage size
VI	change the way it interacts to influence III's binding affinities
VII	change the way it interacts to influence IX's binding affinities
VIII	present small molecules (such as myc epitope), regulate size of phage or influence shape of phage by changing how it assembles into a coat, this could involve changing its interactions with V
IX	present larger molecules, influence the way DNA is packaged, perhaps thereby controlling proliferation
X	changes to II will cause changes to X, perhaps a dual control mechanism
XI	changes to I's interactions with IV will automatically change XI