User:Modesto Redrejo Rodríguez
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Contact Info
- Modesto Redrejo Rodriguez, PhD
DNA Repair Group
Institut Gustave Roussy
UMR8200, Stabilité Génétique et Oncogenèse
39, Rue Camille Desmoulins
94805 - Villejuif CEDEX
FRANCE
Education
- 2009, PhD, Universidad Autónoma de Madrid
- 2005, MS, Universidad Autónoma de Madrid
- 2002, BS, Universidad de Extremadura
Research interests
- DNA replication
- DNA damage and repair
- Base excision and nucleotide incision repair pathways
- AP endonucleases and DNA Glycosylases
- Mutagenic agents
- DNA virus genome maintenance
- Redox modulation of enzyme activities
- Disulfide bonds
Publications
- Gelin A, Redrejo-Rodríguez M, Laval J, Fedorova OS, Saparbaev M, and Ishchenko AA. Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity. PLoS One. 2010 Aug 17;5(8):e12241. DOI:10.1371/journal.pone.0012241 |
DNA Base excision repair (postdoc stage)
- Rodríguez I, Nogal ML, Redrejo-Rodríguez M, Bustos MJ, and Salas ML. The African swine fever virus virion membrane protein pE248R is required for virus infectivity and an early postentry event. J Virol. 2009 Dec;83(23):12290-300. DOI:10.1128/JVI.01333-09 |
- Redrejo-Rodríguez M, Ishchenko AA, Saparbaev MK, Salas ML, and Salas J. African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA. Virology. 2009 Jul 20;390(1):102-9. DOI:10.1016/j.virol.2009.04.021 |
- Redrejo-Rodríguez M, García-Escudero R, Yáñez-Muñoz RJ, Salas ML, and Salas J. African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages. J Virol. 2006 May;80(10):4847-57. DOI:10.1128/JVI.80.10.4847-4857.2006 |
- Rodríguez I, Redrejo-Rodríguez M, Rodríguez JM, Alejo A, Salas J, and Salas ML. African swine fever virus pB119L protein is a flavin adenine dinucleotide-linked sulfhydryl oxidase. J Virol. 2006 Apr;80(7):3157-66. DOI:10.1128/JVI.80.7.3157-3166.2006 |
My work in ASFV
No PubMed papers:
1. Modesto Redrejo-Rodriguez, Adrian Tejeda-Cano, Maria del Carmen Pinto, Pedro Macías.
Lipoxygenase inhibition by flavonoids: semiempirical study of the structure–activity relationship
Journal of Molecular Structure: THEOCHEM, Volume 674, Issues 1-3, April 2004, Pages 121-124
[Paper1]
