User:Megan N McClean
- Megan N McClean
- Princeton University
- 120 Carl Icahn Laboratory
- Princeton, NJ 08544 USA
- Email me through OpenWetWare
I am a Lewis-Sigler fellow at Princeton University.
- 2009, PhD, Harvard
- 2005, MS, Harvard
- 2003, BA, University of California at Berkeley
The McClean lab studies the design principles underlying the signal processing capabilities of biological networks. Cellular signaling networks transmit information about environmental stimuli to the interior of the cell, where successive cellular responses take place. How these networks process their input dictates cellular behavior and fitness. We are interested in how signaling pathways and transcriptional networks are designed to appropriately filter input and set thresholds so that cells respond optimally to changes in their environment. We are also interested in understanding how these networks are adapted and fine-tuned throughout development (short timescale) or evolution (long timescale). The lab takes an experimental approach combining microfluidics with microscopy to monitor the responses of signaling pathways to complex stimuli.
Please check out my Princeton webpage here: McClean Lab at Princeton
Check out our lab webpage on openwetware here: McClean Lab on Openwetware
- Hersen P, McClean MN, Mahadevan L, and Ramanathan S. . pmid:18480263.
- McClean MN, Mody A, Broach JR, and Ramanathan S. . pmid:17259986.
- McClean MN, Hersen P, and Ramanathan S. . pmid:19177008.
- Hersen P, McClean M, and Ramanathan S. . pmid:19116106.