User:Megan N McClean: Difference between revisions
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*Megan N McClean | *Megan N McClean | ||
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Cameron changed this on 6/2/2015 | |||
*Princeton University | *Princeton University | ||
*120 Carl Icahn Laboratory | *120 Carl Icahn Laboratory | ||
*Princeton, NJ 08544 USA | *Princeton, NJ 08544 USA --> | ||
*University of Wisconsin | |||
*Engineering Centers Building 3156 | |||
*1550 Engineering Drive | |||
*Madison, WI 53706 | |||
*[[Special:Emailuser/Megan N McClean|Email me through OpenWetWare]] | *[[Special:Emailuser/Megan N McClean|Email me through OpenWetWare]] | ||
I am a Lewis-Sigler fellow at Princeton University. | <!--I am a Lewis-Sigler fellow at Princeton University.--> | ||
I am an assistant professor at the University of Wisconsin. | |||
==Education== | ==Education== | ||
<!--Include info about your educational background--> | <!--Include info about your educational background--> | ||
* 2009-2014, Lewis-Sigler Fellow, Princeton University<!-- Added by Cameron 6/2/2015--> | |||
* 2009, PhD, Harvard | * 2009, PhD, Harvard | ||
* 2005, MS, Harvard | * 2005, MS, Harvard | ||
Latest revision as of 13:56, 2 June 2015
Contact Info
- Megan N McClean
- University of Wisconsin
- Engineering Centers Building 3156
- 1550 Engineering Drive
- Madison, WI 53706
- Email me through OpenWetWare
I am an assistant professor at the University of Wisconsin.
Education
- 2009-2014, Lewis-Sigler Fellow, Princeton University
- 2009, PhD, Harvard
- 2005, MS, Harvard
- 2003, BA, University of California at Berkeley
Research interests
The McClean lab studies the design principles underlying the signal processing capabilities of biological networks. Cellular signaling networks transmit information about environmental stimuli to the interior of the cell, where successive cellular responses take place. How these networks process their input dictates cellular behavior and fitness. We are interested in how signaling pathways and transcriptional networks are designed to appropriately filter input and set thresholds so that cells respond optimally to changes in their environment. We are also interested in understanding how these networks are adapted and fine-tuned throughout development (short timescale) or evolution (long timescale). The lab takes an experimental approach combining microfluidics with microscopy to monitor the responses of signaling pathways to complex stimuli.
Please check out my Princeton webpage here: McClean Lab at Princeton
Check out our lab webpage on openwetware here: McClean Lab on Openwetware
Publications
- Hersen P, McClean MN, Mahadevan L, and Ramanathan S. Signal processing by the HOG MAP kinase pathway. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7165-70. DOI:10.1073/pnas.0710770105 |
- McClean MN, Mody A, Broach JR, and Ramanathan S. Cross-talk and decision making in MAP kinase pathways. Nat Genet. 2007 Mar;39(3):409-14. DOI:10.1038/ng1957 |
- McClean MN, Hersen P, and Ramanathan S. In vivo measurement of signaling cascade dynamics. Cell Cycle. 2009 Feb 1;8(3):373-6. DOI:10.4161/cc.8.3.7450 |
- Hersen P, McClean M, and Ramanathan S. [Dynamic analysis of cell signalling: the example of the Saccharomyces cerevisiae osmotic response]. Med Sci (Paris). 2008 Dec;24(12):1020-2. DOI:10.1051/medsci/200824121020 |
