User:Megan N McClean

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==Research interests==
==Research interests==
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# Cellular decision-making processes
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The McClean lab studies the design principles underlying the signal processing capabilities of biological networks. Cellular signaling networks transmit information about environmental stimuli to the interior of the cell, where successive cellular responses take place. How these networks process their input dictates cellular behavior and fitness. We are interested in how signaling pathways and transcriptional networks are designed to appropriately filter input and set thresholds so that cells respond optimally to changes in their environment. We are also interested in understanding how these networks are adapted and fine-tuned throughout development (short timescale) or evolution (long timescale). The lab takes an experimental approach combining microfluidics with microscopy to monitor the responses of signaling pathways to complex stimuli.
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# In vivo kinetics of signaling cascades
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Please check out my lab webpage here: [http://www.princeton.edu/genomics/mcclean/ McClean Lab at Princeton ]
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Please check out my Princeton webpage here: [http://www.princeton.edu/genomics/mcclean/ McClean Lab at Princeton ]
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or here: [http://openwetware.org/wiki/McClean McClean Lab on Openwetware]]
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Check out our lab webpage on openwetware here: [http://openwetware.org/wiki/McClean McClean Lab on Openwetware]]
==Publications==
==Publications==

Revision as of 07:58, 3 November 2011

Contents

Contact Info

Contact Info

Megan N. McClean
Megan N. McClean


I am a Lewis-Sigler fellow at Princeton University.


Education

  • 2009, PhD, Harvard
  • 2005, MS, Harvard
  • 2003, BA, University of California at Berkeley

Research interests

The McClean lab studies the design principles underlying the signal processing capabilities of biological networks. Cellular signaling networks transmit information about environmental stimuli to the interior of the cell, where successive cellular responses take place. How these networks process their input dictates cellular behavior and fitness. We are interested in how signaling pathways and transcriptional networks are designed to appropriately filter input and set thresholds so that cells respond optimally to changes in their environment. We are also interested in understanding how these networks are adapted and fine-tuned throughout development (short timescale) or evolution (long timescale). The lab takes an experimental approach combining microfluidics with microscopy to monitor the responses of signaling pathways to complex stimuli.

Please check out my Princeton webpage here: McClean Lab at Princeton

Check out our lab webpage on openwetware here: McClean Lab on Openwetware]

Publications

  1. Paper PMID 18480263
  2. Paper PMID 17259986
  3. Paper PMID 19177008
  4. Paper PMID 19116106

Useful links

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