User:Maureen McKeague: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
| Line 3: | Line 3: | ||
'''Maureen McKeague''' | '''Maureen McKeague''' | ||
<br>[http://www.stanford.edu/ Stanford University] | <br>[http://www.stanford.edu/ Stanford University] | ||
<br>Shriram Center, Room | <br>Shriram Center, Room 256 | ||
<br> Mail Code 4245 | <br> Mail Code 4245 | ||
<br>443 Via Ortega | <br>443 Via Ortega | ||
Revision as of 07:52, 6 January 2015
Contact Info
Maureen McKeague
Stanford University
Shriram Center, Room 256
Mail Code 4245
443 Via Ortega
Stanford, CA 94305
Email me through OpenWetWare
I work in the Smolke lab
Education
- 2007-2012: PhD in Chemistry,Carleton University in the DeRosa lab
- 2003-2007: BSc in Biochemistry and Biotechnology, Carleton University
Research interests
My past, current, and future research aims to improve the workflow of the selection and characterization of small molecule-binding aptamers towards the ultimate goal of developing both in vitro and in vivo biosensors that link important metabolite concentrations to readily detectable signals for high throughput screening and diagnostics.
Publications
- Chang, A.L.; McKeague, M.; Smolke, C.D. Facile characterization of aptamer kinetic and equilibrium binding properties using surface plasmon resonance In: Burke-Aguero, D., editor. Methods in Enzymology. 2014, 549, 451-466.
- McKeague, M.; DeRosa, M.C. Aptamers and SELEX: Tools for the Development of Transformative Molecular Recognition Technology, Aptamers and Synthetic Antibodies, 2014, 1 (1), 12-16.
- McKeague, M.; Ranganathan, V.; Hill, K.; Bardozy, V.; Mezaros, T.; DeRosa, M.C. Selection and Characterization of a Novel DNA Aptamer For Label-Free Fluorescence Biosensing of Ochratoxin A, Toxins, 2014, 6 (8), 2435-2452.
- Chang A.L.; McKeague, M.; Liang, J.C.; Smolke, C.D. Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform, Analytical Chemistry, 2014, 86 (7), 3273–3278.
- Mastronardi, E.; McKeague, M.; Monreal, C.; DeRosa, M.C. Development and Application of Crop Exudate Specific Aptamers, Journal of Biomolecular Structure and Dynamics, 2013, 31 (1), 89.
- McKeague, M.; Foster, A.; Miguel, Y.; Giamberardino, A.; Verdin, C.; Chan, J.Y.; DeRosa, M.C. Development of a DNA aptamer for direct and selective homocysteine detection in human serum, RSC Advances, 2013, 3 (46), 24415-24422.
- McKeague, M.; DeRosa, M.C. Challenges and Opportunities for Small Molecule Aptamer Development, Journal of Nucleic Acids, 2012.
- Cruz-Toledo, J.; McKeague, M.; Zhang, X.; Giamberardino, A.; McConnell, E.; Francis, T.; DeRosa, M.C.; Dumontier, M. Aptamer Base: A collaborative knowledge base to describe aptamers and SELEX experiments. Database: Journal of Biological Databases and Curation. 2012.
- McKeague, M.; Giamberardino, A.; DeRosa, M.C. Advances in Aptamer-Based Biosensors for Food Safety, Environmental Biosensors. 2011, Vernon Somerset (Ed.) ISBN: 9789533074863, InTech. DOI:10.5772/22350
- De Girolamo, A.; McKeague, M.; Miller, J.D.; DeRosa, M.C.; Visconti, A. Determination of Ochratoxin A in Wheat After Clean-Up through a DNA Aptamer-Based Solid Phase Extraction Column. Food Chem. 2011, 127 (3), 1378-1384.
- McKeague, M.; Bradley, C.R.; De Girolamo, A.; Visconti, A.; Miller, J.D.; Derosa, M.C. Screening and Initial Binding Assessment of Fumonisin B(1) Aptamers. Int. J. Mol. Sci. 2010, 11 (12), 4864-4881.
- Luo, X.; McKeague, M.; Pitre, S.; Dumontier, M.; Green, J.; Golshani, A.; Derosa, M.C.; Dehne, F. Computational Approaches Toward the Design of Pools for the in Vitro Selection of Complex Aptamers. RNA. 2010, 16 (11), 2252-2262.
Useful links
- New search engine for aptamers! Aptamer Base
- Dance Your PhD 2010 SELEX Dance
- My LinkedIn profile
- Full curriculum vitae
