User:Maureen McKeague: Difference between revisions

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==Contact Info==
==Contact Info==
[[Image:OWWEmblem.png|thumb|right|Maureen McKeague (an artistic interpretation)]]
[[Image:Photo_16.JPG|thumb|right|Maureen McKeague]]
 
'''Maureen McKeague'''
*Maureen McKeague
<br>[http://www.stanford.edu/ Stanford University]
*Carleton University
<br>Shriram Center, Room 244
*Address 1
<br> Mail Code 4245
*Address 2
<br>443 Via Ortega
*City, State, Country etc.
<br>Stanford, CA 94305
*[[Special:Emailuser/Maureen McKeague|Email me through OpenWetWare]]
<br>[[Special:Emailuser/Maureen McKeague|Email me through OpenWetWare]]


I work in the [[Your Lab]] at XYZ University.  I learned about [[OpenWetWare]] from Synthetic Biology Conference, and I've joined because To help maintain my supervisors lab page, protocols, etc.
I work in the [[Smolke]] lab


==Education==
==Education==
<!--Include info about your educational background-->
<!--Include info about your educational background-->
* Year, PhD, Institute
* 2007-2012: PhD in [http://www5.carleton.ca/chemistry/ Chemistry],[http://carleton.ca/ Carleton University] in the [[DeRosa]] lab
* Year, MS, Institute
* 2003-2007: BSc in [http://www1.carleton.ca/biochem/research/biotechnology/ Biochemistry and Biotechnology], [http://carleton.ca/ Carleton University]
* Year, BS, Institute


==Research interests==
==Research interests==
<!-- Feel free to add brief descriptions to your research interests as well -->
My past, current, and future research aims to improve the workflow of the selection and characterization of small molecule-binding aptamers towards the ultimate goal of developing both in vitro and in vivo biosensors that link important metabolite concentrations to readily detectable signals for high throughput screening and diagnostics.
# Interest 1
# Interest 2
# Interest 3


==Publications==
==Publications==
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed -->
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed -->
<biblio>
#Chang A.L.; McKeague, M.; Liang, J.C.; Smolke, C.D. [http://pubs.acs.org/doi/abs/10.1021/ac5001527 Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform], Analytical Chemistry, 2014, 86 (7), 3273–3278.
#Paper1 pmid=6947258
#Mastronardi, E.; McKeague, M.; Monreal, C.; DeRosa, M.C. [http://www.tandfonline.com/doi/abs/10.1080/07391102.2013.786381?queryID=%24%7BresultBean.queryID%7D#.U72ysvldWv8 Development and Application of Crop Exudate Specific Aptamers], Journal of Biomolecular Structure and Dynamics, 2013, 31, 89.
#Paper2 pmid=13718526
#McKeague, M.; Foster, A.; Miguel, Y.; Giamberardino, A.; Verdin, C.; Chan, J.Y.; DeRosa, M.C. [http://pubs.rsc.org/en/content/articlelanding/2013/ra/c3ra43893g#!divAbstract/ Development of a DNA aptamer for direct and selective homocysteine detection in human serum], RSC Advances, 2013, 3, 24415-24422.
// leave a comment about a paper here
#McKeague, M.; DeRosa, M.C. [http://www.hindawi.com/journals/jna/2012/748913/cta/ Challenges and Opportunities for Small Molecule Aptamer Development], Journal of Nucleic Acids, 2012.
#Book1 isbn=0879697164
#Cruz-Toledo, J.; McKeague, M.; Zhang, X.; Giamberardino, A.; McConnell, E.; Francis, T.; DeRosa, M.C.; Dumontier, M. [http://database.oxfordjournals.org/content/2012/bas006.full Aptamer Base: A collaborative knowledge base to describe aptamers and SELEX experiments]. Database: Journal of Biological Databases and Curation. 2012. 
</biblio>
#McKeague, M.; Giamberardino, A.; DeRosa, M.C. [http://www.intechopen.com/articles/show/title/advances-in-aptamer-based-biosensors-for-food-safety Advances in Aptamer-Based Biosensors for Food Safety], Environmental Biosensors. 2011, Vernon Somerset (Ed.) ISBN: 9789533074863, InTech.
#De Girolamo, A.; McKeague, M.; Miller, J.D.; DeRosa, M.C.; Visconti, A. [http://www.sciencedirect.com/science/article/pii/S0308814611002147 Determination of Ochratoxin A in Wheat After Clean-Up through a DNA Aptamer-Based Solid Phase Extraction Column]. Food Chem. 2011, 127, 1378-1384.
#McKeague, M.; Bradley, C.R.; De Girolamo, A.; Visconti, A.; Miller, J.D.; Derosa, M.C. [http://www.mdpi.com/1422-0067/11/12/4864/ Screening and Initial Binding Assessment of Fumonisin B(1) Aptamers]. Int. J. Mol. Sci. 2010, 11, 4864-4881.
#Luo, X.; McKeague, M.; Pitre, S.; Dumontier, M.; Green, J.; Golshani, A.; Derosa, M.C.; Dehne, F. [http://rnajournal.cshlp.org/content/16/11/2252.long Computational Approaches Toward the Design of Pools for the in Vitro Selection of Complex Aptamers]. RNA. 2010, 16, 2252-2262.


==Useful links==
==Useful links==
*[[OpenWetWare:Welcome|Introductory tutorial]]
*New search engine for aptamers! [http://aptamerbase.semanticscience.org/ Aptamer Base]
*[[Help|OpenWetWare help pages]]
*Dance Your PhD 2010 [https://vimeo.com/14528924/ SELEX Dance]
*My [http://www.linkedin.com/pub/maureen-mckeague/26/b59/645/ LinkedIn] profile

Revision as of 15:11, 18 July 2014

Contact Info

Maureen McKeague

Maureen McKeague
Stanford University
Shriram Center, Room 244
Mail Code 4245
443 Via Ortega
Stanford, CA 94305
Email me through OpenWetWare

I work in the Smolke lab

Education

Research interests

My past, current, and future research aims to improve the workflow of the selection and characterization of small molecule-binding aptamers towards the ultimate goal of developing both in vitro and in vivo biosensors that link important metabolite concentrations to readily detectable signals for high throughput screening and diagnostics.

Publications

  1. Chang A.L.; McKeague, M.; Liang, J.C.; Smolke, C.D. Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform, Analytical Chemistry, 2014, 86 (7), 3273–3278.
  2. Mastronardi, E.; McKeague, M.; Monreal, C.; DeRosa, M.C. Development and Application of Crop Exudate Specific Aptamers, Journal of Biomolecular Structure and Dynamics, 2013, 31, 89.
  3. McKeague, M.; Foster, A.; Miguel, Y.; Giamberardino, A.; Verdin, C.; Chan, J.Y.; DeRosa, M.C. Development of a DNA aptamer for direct and selective homocysteine detection in human serum, RSC Advances, 2013, 3, 24415-24422.
  4. McKeague, M.; DeRosa, M.C. Challenges and Opportunities for Small Molecule Aptamer Development, Journal of Nucleic Acids, 2012.
  5. Cruz-Toledo, J.; McKeague, M.; Zhang, X.; Giamberardino, A.; McConnell, E.; Francis, T.; DeRosa, M.C.; Dumontier, M. Aptamer Base: A collaborative knowledge base to describe aptamers and SELEX experiments. Database: Journal of Biological Databases and Curation. 2012.
  6. McKeague, M.; Giamberardino, A.; DeRosa, M.C. Advances in Aptamer-Based Biosensors for Food Safety, Environmental Biosensors. 2011, Vernon Somerset (Ed.) ISBN: 9789533074863, InTech.
  7. De Girolamo, A.; McKeague, M.; Miller, J.D.; DeRosa, M.C.; Visconti, A. Determination of Ochratoxin A in Wheat After Clean-Up through a DNA Aptamer-Based Solid Phase Extraction Column. Food Chem. 2011, 127, 1378-1384.
  8. McKeague, M.; Bradley, C.R.; De Girolamo, A.; Visconti, A.; Miller, J.D.; Derosa, M.C. Screening and Initial Binding Assessment of Fumonisin B(1) Aptamers. Int. J. Mol. Sci. 2010, 11, 4864-4881.
  9. Luo, X.; McKeague, M.; Pitre, S.; Dumontier, M.; Green, J.; Golshani, A.; Derosa, M.C.; Dehne, F. Computational Approaches Toward the Design of Pools for the in Vitro Selection of Complex Aptamers. RNA. 2010, 16, 2252-2262.

Useful links