User:Marnix H. Medema
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<ul><li>Medema MH, Breitling R, Takano E (2011) The future of industrial antibiotic production: from random mutagenesis to synthetic biology. Bioengineered Bugs, in press [http://www.es.landesbioscience.com/journals/biobugs/article/16114/]<br></ul> | <ul><li>Medema MH, Breitling R, Takano E (2011) The future of industrial antibiotic production: from random mutagenesis to synthetic biology. Bioengineered Bugs, in press [http://www.es.landesbioscience.com/journals/biobugs/article/16114/]<br></ul> | ||
<ul><li>Medema MH, Blin K, Cimermancic P, de Jager V, Zakrzewski P, Fischbach MA, Weber T, Takano E, Breitling R (2011) antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences. Nucleic Acids Research, advance access [http://www.ncbi.nlm.nih.gov/pubmed/21672958]<br></ul> | <ul><li>Medema MH, Blin K, Cimermancic P, de Jager V, Zakrzewski P, Fischbach MA, Weber T, Takano E, Breitling R (2011) antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences. Nucleic Acids Research, advance access [http://www.ncbi.nlm.nih.gov/pubmed/21672958]<br></ul> | ||
| - | <ul><li>Rottig M, Medema MH, Blin K, Rausch C, Weber T, Kohlbacher O (2011) NRPSPredictor2 -- a web server for predicting NRPS adenylation domain specificity. Nucleic Acids Research, advance access. [http://www.ncbi.nlm.nih.gov/pubmed/ | + | <ul><li>Rottig M, Medema MH, Blin K, Rausch C, Weber T, Kohlbacher O (2011) NRPSPredictor2 -- a web server for predicting NRPS adenylation domain specificity. Nucleic Acids Research, advance access. [http://www.ncbi.nlm.nih.gov/pubmed/21558170]<br></ul> |
<ul><li>Medema MH*, Breitling R, Takano E (2011) Synthetic biology in Streptomyces bacteria. Methods in Enzymology 497: 485-502. [http://www.ncbi.nlm.nih.gov/pubmed/21601100]<br></ul> | <ul><li>Medema MH*, Breitling R, Takano E (2011) Synthetic biology in Streptomyces bacteria. Methods in Enzymology 497: 485-502. [http://www.ncbi.nlm.nih.gov/pubmed/21601100]<br></ul> | ||
<ul><li>Medema MH*, Alam MT*, Heijne WH, van den Berg MA, Müller U, Trefzer A, Bovenberg RA, Breitling R, Takano E (2011) Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus. Microbial Biotechnology 4(2): 300-305. [http://www.ncbi.nlm.nih.gov/pubmed/21342474]<br></ul> | <ul><li>Medema MH*, Alam MT*, Heijne WH, van den Berg MA, Müller U, Trefzer A, Bovenberg RA, Breitling R, Takano E (2011) Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus. Microbial Biotechnology 4(2): 300-305. [http://www.ncbi.nlm.nih.gov/pubmed/21342474]<br></ul> | ||
Revision as of 06:19, 17 June 2011
I am a new member of OpenWetWare!
Contents |
Contact Info
- Marnix H. Medema
- University of Groningen
- Kerklaan 30
- 9751NN
- Haren, The Netherlands
- Email me through OpenWetWare
I work in the Department of Microbial Physiology and the Groningen Bioinformatics Centre at the University of Groningen, as a Ph.D. student on a project on genome mining and synthetic biology of microbial secondary metabolites.
Education
- 2008, M.Sc. Biomolecular Sciences, University of Groningen
- 2006, B.Sc. Biology, Radboud University Nijmegen
Research interests
- Comparative and Evolutionary Genomics
- Antibiotics, Natural Products
- Synthetic Biology
- Streptomyces Biology
Publications
- Medema MH, Breitling R, Takano E (2011) The future of industrial antibiotic production: from random mutagenesis to synthetic biology. Bioengineered Bugs, in press [1]
- Medema MH, Blin K, Cimermancic P, de Jager V, Zakrzewski P, Fischbach MA, Weber T, Takano E, Breitling R (2011) antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences. Nucleic Acids Research, advance access [2]
- Rottig M, Medema MH, Blin K, Rausch C, Weber T, Kohlbacher O (2011) NRPSPredictor2 -- a web server for predicting NRPS adenylation domain specificity. Nucleic Acids Research, advance access. [3]
- Medema MH*, Breitling R, Takano E (2011) Synthetic biology in Streptomyces bacteria. Methods in Enzymology 497: 485-502. [4]
- Medema MH*, Alam MT*, Heijne WH, van den Berg MA, Müller U, Trefzer A, Bovenberg RA, Breitling R, Takano E (2011) Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus. Microbial Biotechnology 4(2): 300-305. [5]
- Medema MH, Breitling R, Bovenberg R, Takano E (2011) Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms. Nature Reviews Microbiology 9(2): 131-137. [6]
- Medema MH, Trefzer A, Kovalchuk A, van den Berg M, Müller U, Heijne W, Wu L, Alam MT, Ronning CM, Nierman WC, Bovenberg RA, Breitling R, Takano E (2010) The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways. Genome Biology and Evolution 2: 212-224. [7]
- Medema MH*, Zhou M*, van Hijum SA, Gloerich J, Wessels HJ, Siezen RJ, Strous M (2010) A predicted physicochemically distinct sub-proteome associated with the intracellular organelle of the anammox bacterium Kuenenia stuttgartiensis. BMC Genomics 11: 299. [8]
- van Hijum SA*, Medema MH*, Kuipers OP (2009) Mechanisms and evolution of control logic in prokaryotic transcriptional regulation. Microbiology and Molecular Biology Reviews 73(3): 481-509. [9]
- Ettwig KF, Shima S, van de Pas-Schoonen KT, Kahnt J, Medema MH, Op den Camp HJ, Jetten MS, Strous M (2008) Denitrifying bacteria anaerobically oxidize methane in the absence of Archaea. Environmental Microbiology 10(11): 3164-3173. [10]
*Contributed equally
