User:Marie-Eve Val

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[[Image:Vibriohealthy.jpg|400px|thumb|Vibrio cholerae|border]]
[[Image:Vibriohealthy.jpg|400px|thumb|Vibrio cholerae|border]]
[[Image:fusion.jpg|600px|thumb|right|site-specific recombination-based engineering tool to massively reorganize V. cholerae's genome|border]]
[[Image:fusion.jpg|600px|thumb|right|site-specific recombination-based engineering tool to massively reorganize V. cholerae's genome|border]]
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[[Image:blue.jpg|400px|thumb|Genome rearrangement events occuring within a single colony|border]]
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[[Image:MCH1chrrec.jpg|400px|thumb|Genome rearrangement events occuring within a single colony|border]]
<font size="3">'''Marie-Eve VAL'''</font size><br/><font size="2">INSTITUT PASTEUR<br/>Unité "Plasticité du Génome Bactérien"<br/>Département  Génomes et Génétique<br/>CNRS URA2171<br/>25 rue du Dr. Roux<br/>
<font size="3">'''Marie-Eve VAL'''</font size><br/><font size="2">INSTITUT PASTEUR<br/>Unité "Plasticité du Génome Bactérien"<br/>Département  Génomes et Génétique<br/>CNRS URA2171<br/>25 rue du Dr. Roux<br/>
75724 PARIS cedex 15<br/>FRANCE<br/>[[Special:Emailuser/Marie-Eve_Val|Email me through OpenWetWare]]
75724 PARIS cedex 15<br/>FRANCE<br/>[[Special:Emailuser/Marie-Eve_Val|Email me through OpenWetWare]]
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*2003 - '''Engineering degree in biotechnology and Master in cellular and molecular biology''' <br/>[http://www-esbs.u-strasbg.fr/esbs/?lang=en ESBS (Strasbourg, Freiburg, Karlsruhe and Basel)]
*2003 - '''Engineering degree in biotechnology and Master in cellular and molecular biology''' <br/>[http://www-esbs.u-strasbg.fr/esbs/?lang=en ESBS (Strasbourg, Freiburg, Karlsruhe and Basel)]
*1999 - '''Technician degree in Biotechnology '''<br/>LVC (Gif-sur-Yvette)
*1999 - '''Technician degree in Biotechnology '''<br/>LVC (Gif-sur-Yvette)
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== Professional Training ==
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==Professional Training==
* Since 2009 - '''Post-Doctoral research training'''<br/> [http://www.pasteur.fr/ip/easysite/pasteur/fr Institut Pasteur (Paris)] - [[Mazel| Didier Mazel's lab]]<br/>
* Since 2009 - '''Post-Doctoral research training'''<br/> [http://www.pasteur.fr/ip/easysite/pasteur/fr Institut Pasteur (Paris)] - [[Mazel| Didier Mazel's lab]]<br/>
* 2004 / 2008 - '''PhD Thesis'''<br/>[http://www.cgm.cnrs-gif.fr/version_gb/index_gb.html Centre de Génétique Moléculaire (Gif-sur-Yvette)] , [http://www.cgm.cnrs-gif.fr/barre/index_gb.html Francois-Xavier Barre's lab]<br/>
* 2004 / 2008 - '''PhD Thesis'''<br/>[http://www.cgm.cnrs-gif.fr/version_gb/index_gb.html Centre de Génétique Moléculaire (Gif-sur-Yvette)] , [http://www.cgm.cnrs-gif.fr/barre/index_gb.html Francois-Xavier Barre's lab]<br/>
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<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed -->
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<biblio>
<biblio>
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#Genome_Engineering_in_Vibrio_cholerae_2012 pmid=22253612  
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# PLOS-Genetics-2012 pmid=22253612  
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// Genome Engineering in Vibrio cholerae: A Feasible Approach to Address Biological Issues.
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// Genome Engineering in Vibrio cholerae: A Feasible Approach to Address Biological Issues
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#Paper2 pmid=20133778  
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# PNAS-2010 pmid=20133778  
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// Molecular keys of the tropism of integration of the cholera toxin phage.
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// Molecular keys of the tropism of integration of the cholera toxin phage
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#Paper3 pmid=19525356
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# Genome-Research-2009 pmid=19525356
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// Comparative genomics of protoploid Saccharomycetaceae.
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// Comparative genomics of protoploid Saccharomycetaceae  
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#Paper4 pmid=18818731  
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# PLOS-Genetics-2008 pmid=18818731  
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// FtsK-dependent dimer resolution on multiple chromosomes in the pathogen Vibrio cholerae.
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// FtsK-dependent dimer resolution on multiple chromosomes in the pathogen Vibrio cholerae
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#Paper5 pmid=16109379  
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# Molecular-Cell-2005 pmid=16109379
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// The single-stranded genome of phage CTX is the form used for integration into the genome of Vibrio cholerae.
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// The single-stranded genome of phage CTX is the form used for integration into the genome of Vibrio cholerae
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</biblio>
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</biblio>
 
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<biblio>
 
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#Synthetic-Integron-2010 pmid=20534632
 
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#attC-2010 pmid=19730680
 
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#Weak-Root-2009 pmid=19179528
 
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#iGEM-Paris-2007 pmid=18466734
 
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</biblio>
 
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Current revision

Vibrio cholerae
Vibrio cholerae
site-specific recombination-based engineering tool to massively reorganize V. cholerae's genome
site-specific recombination-based engineering tool to massively reorganize V. cholerae's genome
Genome rearrangement events occuring within a single colony
Genome rearrangement events occuring within a single colony

Marie-Eve VAL
INSTITUT PASTEUR
Unité "Plasticité du Génome Bactérien"
Département Génomes et Génétique
CNRS URA2171
25 rue du Dr. Roux
75724 PARIS cedex 15
FRANCE
Email me through OpenWetWare

Contents

Research interests

I am a post-doctoral research fellow in Didier Mazel's lab at the Institut Pasteur of Paris. I have a great interest in bacterial genome structuration, organization and maintenance ... and a special interest in multipartite genomes. Owing to its bi-chromosomal genome architecture and its importance in public health, Vibrio cholerae, the causative agent of cholera, has become a preferred model to study bacteria with multipartite genomes. My approach is to drastically alter V. cholerae’s genome structure to gain more insight into multipartite genomes. To do so, I developed a site-specific recombination-based engineering tool, which provides us with a powerful means to massively reorganize in principle any prokaryotic genome. The laboratory of Didier Mazel was an ideal place to initiate such a project since they have developed a large set of genetic tools to work in the vibrios and Didier Mazel has substantial knowledge and experience in site-specific recombination, bacterial genetics and genome analysis.

Education

Professional Training

Publications

  1. Val ME, Skovgaard O, Ducos-Galand M, Bland MJ, and Mazel D. . pmid:22253612. PubMed HubMed [PLOS-Genetics-2012]
    Genome Engineering in Vibrio cholerae: A Feasible Approach to Address Biological Issues

  2. Das B, Bischerour J, Val ME, and Barre FX. . pmid:20133778. PubMed HubMed [PNAS-2010]
    Molecular keys of the tropism of integration of the cholera toxin phage

  3. Génolevures Consortium, Souciet JL, Dujon B, Gaillardin C, Johnston M, Baret PV, Cliften P, Sherman DJ, Weissenbach J, Westhof E, Wincker P, Jubin C, Poulain J, Barbe V, Ségurens B, Artiguenave F, Anthouard V, Vacherie B, Val ME, Fulton RS, Minx P, Wilson R, Durrens P, Jean G, Marck C, Martin T, Nikolski M, Rolland T, Seret ML, Casarégola S, Despons L, Fairhead C, Fischer G, Lafontaine I, Leh V, Lemaire M, de Montigny J, Neuvéglise C, Thierry A, Blanc-Lenfle I, Bleykasten C, Diffels J, Fritsch E, Frangeul L, Goëffon A, Jauniaux N, Kachouri-Lafond R, Payen C, Potier S, Pribylova L, Ozanne C, Richard GF, Sacerdot C, Straub ML, and Talla E. . pmid:19525356. PubMed HubMed [Genome-Research-2009]
    Comparative genomics of protoploid Saccharomycetaceae

  4. Val ME, Kennedy SP, El Karoui M, Bonné L, Chevalier F, and Barre FX. . pmid:18818731. PubMed HubMed [PLOS-Genetics-2008]
    FtsK-dependent dimer resolution on multiple chromosomes in the pathogen Vibrio cholerae

  5. Val ME, Bouvier M, Campos J, Sherratt D, Cornet F, Mazel D, and Barre FX. . pmid:16109379. PubMed HubMed [Molecular-Cell-2005]
    The single-stranded genome of phage CTX is the form used for integration into the genome of Vibrio cholerae

All Medline abstracts: PubMed HubMed

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