User:LarryGray:Questions: Difference between revisions
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====Moyer et al==== | ====Moyer et al==== | ||
# According to current understanding, what is the most plausible mechanism for CMG component interaction and how could this be tested? | # According to current understanding, what is the most plausible mechanism for CMG component interaction and how could this be tested? | ||
Answer: Phosphorylation by cdks. Could be tested by site-directed mutagenesis of CMG components to eliminate phosphorylation sites and see if interaction remains. | |||
Revision as of 20:02, 24 April 2007
Questions
Week 2
Lopes et al
- What observations lead to the authors' suggestion that discontinuites left randomly behind the fork are not immediately sealed after the passage of the replication fork?
Heller and Marians
- How did the author cleverly show that the same DnaB from the lagging strand was involved in leading strand reinitation?
Week 3
Moyer et al
- According to current understanding, what is the most plausible mechanism for CMG component interaction and how could this be tested?
Answer: Phosphorylation by cdks. Could be tested by site-directed mutagenesis of CMG components to eliminate phosphorylation sites and see if interaction remains.
