User:Keyun Wang/Notebook/Experimental Biological Chemistry I/2012/10/10

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Current revision (23:44, 26 October 2012) (view source)
(Procedure)
 
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* Maestro was used to visualize the molecular structure of adenosine deaminase.
* Maestro was used to visualize the molecular structure of adenosine deaminase.
* Different portions of the molecular structure: ligands, hydrogen bonds, residues, etc. were visualized
* Different portions of the molecular structure: ligands, hydrogen bonds, residues, etc. were visualized
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* Mutations were suggested for site-directed mutagenesis for adenosine deaminase to test the specific amino acid residues in the binding pocket: E28K
+
* Mutations were suggested for site-directed mutagenesis for adenosine deaminase to test the specific amino acid residues in the binding pocket: E34K
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Experimental Biological Chemistry I Main project page
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Purpose

  • Learn about protein modeling and computation through the use of Maestro.
  • Plan research protocol for the rest of semester.

Procedure

  • Maestro was used to visualize the molecular structure of adenosine deaminase.
  • Different portions of the molecular structure: ligands, hydrogen bonds, residues, etc. were visualized
  • Mutations were suggested for site-directed mutagenesis for adenosine deaminase to test the specific amino acid residues in the binding pocket: E34K


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