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Revision as of 21:32, 12 October 2010
<html> <head> <title>Jerzy Szablowski</title> <META NAME="description" CONTENT="Jerzy Szablowski, Sc.B, California Institute of Technology, Bioengineering option."> <META NAME="keywords" CONTENT="iGEM, jerzy, szablowski, mit, caltech, institute of technology, MRI, ferritin, p450, langer, arnold, jasanoff, boyden, iLCD, yeast tv"> </head> </html>
Jerzy Szablowski, S.B.
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I am a Ph.D. student at California Institute of Technology in Bionengineering, currently working with Paul Rothemund [link].
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CV
Education
California Institute of Technology, Pasadena, CA
Current position,
Ph.D. Bioengineering Option, Synthetic and Systems Biology track
Advisor: Paul Rothemund
Massachusetts Institute of Technology, Cambridge, MA Class: 2009, Science Bachelor in Biological Engineering, with minor in Biology and humanities concentration in Psychology.
27th Tadeusz Czacki high school, Warsaw, Poland Class: 2005, Profile: Math and Physics
Awards
• iGEM 2009, 3rd place/112 teams (synthetic standard prize), golden medal, finalist, best new applications area, best experimental measurement (2009)
• Henry and Grazyna Bauer Fellowship for graduate studies (2009)
• BE-BMES/Johnson & Johnson Prize for Excellence in Biomedical Research (2008) [1]
• Direct research funding from MIT Undergraduate Research Opportunities Program - multiple times. (2006-2008)
• Physics Olympiad for secondary school students - finalist (2002).
Research experience
Paul Rothemund research group , California Institute of Technology, Pasadena, CA
graduate research assistant
Designing DNA nano-structures for applications in biophysics and bioelectronics
International Genetically Encoded Machine competition, IGEM Valencia team 2009, Spain
Engineering a cell-based computer monitor.
- originated the idea and designed the basic approach
- Designed an electrical stimulator, software and outline of part of experiments.
Synthetic Neurobiology group (PI: Edward Boyden), MIT Media Lab, Cambridge, MA
Undergraduate research assistant
Engineering Light Activated G-protein coupled receptors
• Started a new project, developed assays and designed new protein chimeras.
• Mentored and trained two undergraduate researchers over the summer;
Frances Arnold Research Group California Inst. of Tech, Pasadena, CA
Undergraduate research assistant (In collaboration with Langer Lab)
Evolution of highly sensitive MRI sensor for Dopamine
• Developed a directed evolution screen for selection of protein based contrast agents for MRI.
• Achieved thermal stabilization of contrast agents.
• Developed statistical analysis methods and models for the screen.
Langer Lab in collaboration with Jasanoff Lab, MIT, Cambridge, MA
Undergraduate research assistant
Functional MRI sensors for noninvasive imaging of Dopamine and kinase activity
• Helped engineering proteins for both sensors. Took part in mutagenesis, testing and design.
• Both projects have been finished and publications are in review.
Department of molecular biology, Intl. Inst. For Molecular and Cell Bio., Warsaw, Poland,
Intern
Functional and structural differences between heat shock protein 90 (Hsp90) variants - Hsp90a and Hsp90b
• Performed molecular biology and tissue culture experiments.
Publications
1. Cristina Vilanova, Ángeles Hueso, Carles Palanca, Guillem Marco,Miguel Pitarch, Eduardo Otero, Juny Crespo, Jerzy Szablowski, Sara Rivera,Laura Domínguez-Escribà, Emilio Navarro, Arnau Montagud, Pedro Fernández de Córdoba, Asier González, Joaquín Ariño,Andrés Moya, Javier Urchueguía & Manuel Porcar, "Aequorin-expressing yeast emits light under
electric control" , (in review)
2. Shapiro MG*, Westmeyer GG*, Romero P, Szablowski JO, Küster B, Shah A, Otey CR, Langer R, Arnold FH, & Jasanoff AP, “Directed evolution of an MRI contrast agent for noninvasive imaging of dopamine. Nature Biotechnology. 28 February 2010. DOI: 10.1038/nbt.1609 [link]
3. Shapiro MG, Szablowski JO, Langer R, Jasanoff AP, Protein nanoparticles engineered to sense kinase activity in MRI, Journal of the American Chemical Society 2009 131 (7), 2484-2486 [link]
Presentations
1. Jerzy Szablowski, Bioengineering and Biological Engineering,23.09.2010, 14th Science Festival in Warsaw [1]
2. Jerzy Szablowski, Protein Engineering or how to make your own enzymes, 23.09.2010, 14th Science Festival in Warsaw [2]
3. Westmeyer GG, Shapiro MG, Romero P, Szablowski JO, Otey C, Arnold FH, Jasanoff AP, Imaging Dopamine in the Brain With a Novel MRI Contrast Agent, World Molecular Imaging Congress, sept 24th, 2009 [link]
4. Jerzy Szablowski, Magnetic Resonance Imaging, (2007), The Biotech, vol.5, 5:1-9
5. Mikhail G. Shapiro, Philip Romero, Jerzy Szablowski, Robert Langer, Frances H. Arnold, Alan Jasanoff, Development of Genetically Encoded Molecular Sensor for Non-Invasive Imaging of Dopamine Using MRI,(2006) The fifth Annual Meeting of the Society for Molecular Imaging.
Press Releases
yeast monitor: concept proposed to Valencia team in May 2009; later developed for 2009 iGEM competition.
Polish:
http://www.dziennik.pl/nauka/article476896/Polak_wymyslil_zywy_monitor_z_drozdzy.html
http://gadzetomania.pl/2009/11/10/polak-potrafi-czyli-monitor-z-drozdzy
http://www.sfora.pl/Polski-naukowiec-wymyslil-monitor-z-drozdzy-a13523
English:
http://www.msnbc.msn.com/id/33728433/ns/technology_and_science-science/
Spanish:
http://www.elpais.com/articulo/sociedad/Levaduras/funcionan/pixeles/elpepuespval/20091103elpepusoc_9/Tes
http://www.laciberprensa.com/ultimas/universitaria/3980.html
http://www.que.es/valencia/200908311313-estudiantes-valencianos-utilizan-medusas-crear.html
http://www.lasprovincias.es/valencia/20090901/vida-ocio/television-hecha-medusas-20090901.html
http://www.neoteo.com/televisores-hechos-con-celulas-16191.neo
http://noticias.terra.es/local/2009/0603/actualidad/estudiantes-valencianos-de-la-upv-y-la-uv-crearan-una-pantalla-de-television-a-partir-de-celulas.aspx
http://www.adn.es/local/valencia/20090603/NWS-0423-Estudiantes-valencianos-television-pantalla-crearan.html
http://www.elmundo.es/elmundo/2009/06/03/television/1244024480.html
http://www.levante-emv.com/secciones/noticia.jsp?pRef=2009060300_40_597302__Tecnologia-Estudiantes-valencianos-crearan-pantalla-television-partir-celulas
http://www.dailynews.rs/news/2009/08/valencia-students-used-jellyfish-to-create-a-tv-screen/
http://www.antena3noticias.com/PortalA3N/noticia/ciencia-y-tecnologia/Unos-investigadores-intentan-crear-una-pantalla-television-partir-medusas/8149310
http://www.rtvv.es/video/video_informa.asp?id=16092009_pixel.flv
http://www.cpi.upv.es/noticias-y-eventos/noticias-y-eventos-cpi/i/30621/163/una-television-hecha-de-medusas
http://gacetauniversitaria.es/articles/847-una-tele-hecha-con-medusas
http://www.ruvid.org/Fichanoticia.php?id=686
http://www.lavozdebenidorm.com/__n858682__Estudiantes_valencianos_utilizan_medusas_para_crear_una_pantalla_de_television_de_celulas.html
http://www.abc.es/agencias/noticia.asp?noticia=157753
http://www.levante-emv.com/comunitat-valenciana/2009/11/03/cerebros-valencianos-triunfan-oscar-investigacion/647846.html
http://www.intertech.upv.es/pdf/press/091109_elmundo.pdf?q=es/node/1742/
Video chat with questions and answers:
http://videochat.lasprovincias.es/videochat.php?videochat=iGEM09
genetically encoded MRI contrast agent detecting dopamine
http://web.mit.edu/press/2010/brain-imaging.html
http://www.businessweek.com/lifestyle/content/healthday/636459.html
http://www.newscientist.com/article/dn18602-brain-scans-now-catch-chemicals-too.html
http://www.popsci.com/technology/article/2010-03/new-sensors-directly-track-brains-chemical-messengers-first-time
http://www.medicalnewstoday.com/articles/181084.php
http://kopalniawiedzy.pl/dopamina-fMRI-domena-hemowa-cytochrom-P450-neuroprzekaznik-przeplyw-obrazowac-Alan-Jasanoff-9836.html
In Polish
Newsweek: How to get in to universities abroad
will follow
Science Festival in Warsaw
http://supermozg.gazeta.pl/supermozg/1,93139,8428982,Zrob_sobie_procesor_z_DNA.html
Personal Interests
Apart from science and engineering design I enjoy sports - cross country running, skiing, squash and scuba diving.
I am also an avid photographer. Some of my photographs can be viewed here: http://slashpsi.digart.pl/digarty/
If you have an idea and would like to receive some micro-funding, or you would like to support other projects, visit a website founded by my friend: http://sciencefellows.org/
My photographs
http://slashpsi.digart.pl/digarty/ [ website in polish]
Valencia, City of Arts and sciences
California Institute of Technology, Beckmann Auditorium
Edinburgh, UK
Boston, MIT crew on Charles River
Nahant, MA
California Institute of Technology
MIT building Nw35
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