User:Jayajit Das

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Contact Info

  • Jayajit Das

Assistant Professor
Battelle Center for Mathematical Medicine
The Research Institute at Nationwide Children's Hospital
Departments of Pediatrics, Physics, Integrated Biomedical Sciences, and Biophysics Graduate Program
The Ohio State University, Columbus, OH 43205

Email: das.70 @ osu.edu; jayajit.das @ nationwidechildrens.org ; jayajit @ gmail.com
Phone: 614-355-5632 (work)
Fax: 614-355-2928
[DasLab]

Education and Professional Experience

  • 2005-2008 Postdoctoral Fellow, Massachusetts Institute of Technology
  • 2002-2005 Postdoctoral Fellow, University of California at Berkeley
  • 2000-2002 Postdoctoral Fellow, Virginia Institute of Polytechnic and State University
  • 2000 Ph.D. Physics, Raman Research Institute, Bangalore, India
  • 1996 M.Sc. Physics, Institute of Mathematical Sciences, Chennai (Madras) India
  • 1994 B.Sc. Physics, Presidency College, Kolkata(Calcutta), India

My lab uses theoretical and computational approaches based on statistical physics to uncover basic mechanistic principles underlying our innate and adaptive immune response. Obtaining such mechanistic principles from experimental observations alone is often difficult because the pertinent processes include co-operative dynamic events with many participating components. A further complication that confounds intuition is stochastic fluctuations in these systems with small numbers of molecules. However, by synergistically integrating observations from experiments with transgenic animals, single molecule techniques and imaging studies probing molecular events in live animals with these theoretical and computational approaches we can provide system-level understanding into such complex systems. The mechanistic insight gained from such studies not only will help develop future experiments to unravel basic principles of our immune system, but may also help envision therapeutic strategies for infectious diseases and autoimmune disorders.

Lab members

Sayak Mukherjee (Ph.D Physics, V.Tech) Postdoc
Aleya Dhanji Graduate student, OSU Physics Department

Lab Alumni

Michael Dworkin (Math Major, OSU) Undergraduate student
Current Position: Merrimack Pharmaceuticals, Inc

Birra Abdurehman (Math Major, OSU) Undergraduate student
Jagadish Kumar (Postdoc) 2010-2011

Mithila Agnihotri Graduate student, OSU Biophysics Program

Arjun Venkataraman (High School Research Project)

Selected Publications

  1. Das J. . pmid:23298061. PubMed HubMed [Paper1]
  2. Mukherjee S, Zhu J, Zikherman J, Parameswaran R, Kadlecek TA, Wang Q, Au-Yeung B, Ploegh H, Kuriyan J, Das J, and Weiss A. . pmid:23281368. PubMed HubMed [Paper2]
  3. Dworkin M, Mukherjee S, Jayaprakash C, and Das J. . pmid:22378749. PubMed HubMed [Paper3]
  4. Das J. . pmid:20923636. PubMed HubMed [Paper4]
  5. Chakraborty AK and Das J. . pmid:20029448. PubMed HubMed [Paper5]
  6. Das J, Kardar M, and Chakraborty AK. . pmid:19566183. PubMed HubMed [Paper6]
  7. Chakraborty AK, Das J, Zikherman J, Yang M, Govern CC, Ho M, Weiss A, and Roose J. . pmid:19366993. PubMed HubMed [Paper7]
  8. Das J, Ho M, Zikherman J, Govern C, Yang M, Weiss A, Chakraborty AK, and Roose JP. . pmid:19167334. PubMed HubMed [Paper8]
  9. Prasad A, Zikherman J, Das J, Roose JP, Weiss A, and Chakraborty AK. . pmid:19098101. PubMed HubMed [Paper9]
  10. Cemerski S, Das J, Giurisato E, Markiewicz MA, Allen PM, Chakraborty AK, and Shaw AS. . pmid:18760640. PubMed HubMed [Paper10]
  11. Artyomov MN, Das J, Kardar M, and Chakraborty AK. . pmid:18025473. PubMed HubMed [Paper11]
  12. Wylie DC, Das J, and Chakraborty AK. . pmid:17360359. PubMed HubMed [Paper12]
  13. Cemerski S, Das J, Locasale J, Arnold P, Giurisato E, Markiewicz MA, Fremont D, Allen PM, Chakraborty AK, and Shaw AS. . pmid:17346997. PubMed HubMed [Paper13]
All Medline abstracts: PubMed HubMed

Useful links

Google_Scholar_Link

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Jobs

Graduate Student: Students with a background in Physics, Mathematics, Chemistry, Computer Science or Chemical Engineering are encouraged to apply.

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