User:Jayajit Das: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
(38 intermediate revisions by the same user not shown)
Line 1: Line 1:
<!-- Delete this entire line as part of your first edit of your user page --> {{New user}}
==Contact Info==
==Contact Info==
[[Image:Jayajit.jpg|thumb|right|]]  
[[Image:Jayajit.jpg|thumb|right|]]  
Line 9: Line 7:
Battelle Center for Mathematical Medicine<br />
Battelle Center for Mathematical Medicine<br />
The Research Institute at Nationwide Children's Hospital<br />
The Research Institute at Nationwide Children's Hospital<br />
Biophysics Graduate Program and Department of Pediatrics<br />
Departments of Pediatrics, Physics, Integrated Biomedical Sciences, and Biophysics Graduate Program<br />
Ohio State University, Columbus, OH 43205<br />   
The Ohio State University, Columbus, OH 43205<br />   


'''Email''': das.70 @ osu.edu; jayajit.das @ nationwidechildrens.org ; jayajit @ gmail.com <br />
'''Email''': das.70 @ osu.edu; jayajit.das @ nationwidechildrens.org ; jayajit @ gmail.com <br />
'''Phone''': 614-355-4526 (work)<br />
'''Phone''': 614-355-5632 (work)<br />
'''Fax''':  614-355-2928
'''Fax''':  614-355-2928 <br>
[[http://openwetware.org/wiki/Das_Lab DasLab]] <br>


==Education and Professional Experience==
==Education and Professional Experience==
Line 26: Line 25:


My lab uses theoretical and computational approaches based on statistical physics to uncover basic mechanistic principles underlying our innate and adaptive immune response.  Obtaining such mechanistic principles from experimental observations alone is often difficult because the pertinent processes include co-operative dynamic events with many participating components. A further complication that confounds intuition is stochastic fluctuations in these systems with small numbers of molecules. However, by synergistically integrating observations from experiments with transgenic animals, single molecule techniques and imaging studies probing molecular events in live animals with these theoretical and computational approaches we can provide system-level understanding into such complex systems. The mechanistic insight gained from such studies not only will help develop future experiments to unravel basic principles of our immune system, but may also help envision therapeutic strategies for infectious diseases and autoimmune disorders.
My lab uses theoretical and computational approaches based on statistical physics to uncover basic mechanistic principles underlying our innate and adaptive immune response.  Obtaining such mechanistic principles from experimental observations alone is often difficult because the pertinent processes include co-operative dynamic events with many participating components. A further complication that confounds intuition is stochastic fluctuations in these systems with small numbers of molecules. However, by synergistically integrating observations from experiments with transgenic animals, single molecule techniques and imaging studies probing molecular events in live animals with these theoretical and computational approaches we can provide system-level understanding into such complex systems. The mechanistic insight gained from such studies not only will help develop future experiments to unravel basic principles of our immune system, but may also help envision therapeutic strategies for infectious diseases and autoimmune disorders.
== Lab members ==
Sayak Mukherjee (Ph.D Physics, V.Tech) Postdoc <br />
Aleya Dhanji Graduate student, OSU Physics Department  <br />
== Lab Alumni ==
Michael Dworkin (Math Major, OSU) Undergraduate student <br />
Current Position: Merrimack Pharmaceuticals, Inc <br />
Birra Abdurehman (Math Major, OSU) Undergraduate student <br />
Jagadish Kumar (Postdoc) 2010-2011 <br />
Mithila Agnihotri Graduate student, OSU Biophysics Program  <br />
Arjun Venkataraman (High School Research Project) <br />


==Selected Publications==
==Selected Publications==
<biblio>
<biblio>
#Paper1 pmid=19366993
#Paper1 pmid=25473880
#Paper2 pmid=19167334
#Paper2 pmid=25359276
#Paper3 pmid=19098101
#Paper3 pmid=24280043
#Paper4 pmid=18760640
#Paper4 pmid=24164951
#Paper5 pmid=18025473  
#Paper5 pmid=24167288
#Paper6 pmid=17360359
#Paper6 pmid=24066087
#Paper7 pmid=17346997
#Paper7 pmid=23298061
#Paper8 pmid=23281368
#Paper9 pmid=22378749
#Paper10 pmid=20923636
#Paper11 pmid=20029448
#Paper12 pmid=19566183
#Paper13 pmid=19366993
#Paper14 pmid=19167334
#Paper15 pmid=19098101
#Paper16 pmid=18760640
#Paper17 pmid=18025473  
#Paper18 pmid=17360359
#Paper19 pmid=17346997
</biblio>
</biblio>


==Useful links==
==Useful links==
* Detailed CV: [[Image:das_cv_jan_09_web.pdf]]
[http://scholar.google.com/citations?user=iXkBO4MAAAAJ&hl=en&oi=ao  Google_Scholar_Link]


[http://www3.clustrmaps.com/user/b259054d Visitor_Map][img]http://www3.clustrmaps.com/stats/maps-no_clusters/--openwetware.org-wiki-User-Jayajit_Das-thumb.jpg[/img][/url]


*More details at http://www.mathmed.org/#Jayajit_Das


==Jobs==
==Jobs==
'''Graduate Student''': Students with a background in Physics, Mathematics, Chemistry, Computer Science or Chemical Engineering are encouraged to apply.
'''Graduate Student''': Students with a background in Physics, Mathematics, Chemistry, Computer Science or Chemical Engineering are encouraged to apply.

Revision as of 12:57, 26 December 2014

Contact Info

  • Jayajit Das

Assistant Professor
Battelle Center for Mathematical Medicine
The Research Institute at Nationwide Children's Hospital
Departments of Pediatrics, Physics, Integrated Biomedical Sciences, and Biophysics Graduate Program
The Ohio State University, Columbus, OH 43205

Email: das.70 @ osu.edu; jayajit.das @ nationwidechildrens.org ; jayajit @ gmail.com
Phone: 614-355-5632 (work)
Fax: 614-355-2928
[DasLab]

Education and Professional Experience

  • 2005-2008 Postdoctoral Fellow, Massachusetts Institute of Technology
  • 2002-2005 Postdoctoral Fellow, University of California at Berkeley
  • 2000-2002 Postdoctoral Fellow, Virginia Institute of Polytechnic and State University
  • 2000 Ph.D. Physics, Raman Research Institute, Bangalore, India
  • 1996 M.Sc. Physics, Institute of Mathematical Sciences, Chennai (Madras) India
  • 1994 B.Sc. Physics, Presidency College, Kolkata(Calcutta), India

My lab uses theoretical and computational approaches based on statistical physics to uncover basic mechanistic principles underlying our innate and adaptive immune response. Obtaining such mechanistic principles from experimental observations alone is often difficult because the pertinent processes include co-operative dynamic events with many participating components. A further complication that confounds intuition is stochastic fluctuations in these systems with small numbers of molecules. However, by synergistically integrating observations from experiments with transgenic animals, single molecule techniques and imaging studies probing molecular events in live animals with these theoretical and computational approaches we can provide system-level understanding into such complex systems. The mechanistic insight gained from such studies not only will help develop future experiments to unravel basic principles of our immune system, but may also help envision therapeutic strategies for infectious diseases and autoimmune disorders.

Lab members

Sayak Mukherjee (Ph.D Physics, V.Tech) Postdoc
Aleya Dhanji Graduate student, OSU Physics Department

Lab Alumni

Michael Dworkin (Math Major, OSU) Undergraduate student
Current Position: Merrimack Pharmaceuticals, Inc

Birra Abdurehman (Math Major, OSU) Undergraduate student
Jagadish Kumar (Postdoc) 2010-2011

Mithila Agnihotri Graduate student, OSU Biophysics Program

Arjun Venkataraman (High School Research Project)

Selected Publications

Error fetching PMID 25473880:
Error fetching PMID 25359276:
Error fetching PMID 24280043:
Error fetching PMID 24164951:
Error fetching PMID 24167288:
Error fetching PMID 24066087:
Error fetching PMID 23298061:
Error fetching PMID 23281368:
Error fetching PMID 22378749:
Error fetching PMID 20923636:
Error fetching PMID 19566183:
Error fetching PMID 19366993:
Error fetching PMID 19167334:
Error fetching PMID 19098101:
Error fetching PMID 18760640:
Error fetching PMID 18025473:
Error fetching PMID 17360359:
Error fetching PMID 17346997:
  1. Error fetching PMID 25473880: [Paper1]
  2. Error fetching PMID 25359276: [Paper2]
  3. Error fetching PMID 24280043: [Paper3]
  4. Error fetching PMID 24164951: [Paper4]
  5. Error fetching PMID 24167288: [Paper5]
  6. Error fetching PMID 24066087: [Paper6]
  7. Error fetching PMID 23298061: [Paper7]
  8. Error fetching PMID 23281368: [Paper8]
  9. Error fetching PMID 22378749: [Paper9]
  10. Error fetching PMID 20923636: [Paper10]
  11. Chakraborty AK and Das J. Pairing computation with experimentation: a powerful coupling for understanding T cell signalling. Nat Rev Immunol. 2010 Jan;10(1):59-71. DOI:10.1038/nri2688 | PubMed ID:20029448 | HubMed [Paper11]
  12. Error fetching PMID 19566183: [Paper12]
  13. Error fetching PMID 19366993: [Paper13]
  14. Error fetching PMID 19167334: [Paper14]
  15. Error fetching PMID 19098101: [Paper15]
  16. Error fetching PMID 18760640: [Paper16]
  17. Error fetching PMID 18025473: [Paper17]
  18. Error fetching PMID 17360359: [Paper18]
  19. Error fetching PMID 17346997: [Paper19]

All Medline abstracts: PubMed | HubMed

Useful links

Google_Scholar_Link

Visitor_Map[img]http://www3.clustrmaps.com/stats/maps-no_clusters/--openwetware.org-wiki-User-Jayajit_Das-thumb.jpg[/img][/url]

Jobs

Graduate Student: Students with a background in Physics, Mathematics, Chemistry, Computer Science or Chemical Engineering are encouraged to apply.