User:Jarle Pahr/Antibiotics: Difference between revisions
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Notes and links regarding antibiotics: | Notes and links regarding antibiotics: | ||
http://gotsomescienceonyou.com/2013/08/06/resist-the-resistance/ | |||
http://openwetware.org/wiki/Fong:Antibiotics | |||
http://bitesizebio.com/articles/antibiotic-stability-keep-your-gunpowder-dry/ | http://bitesizebio.com/articles/antibiotic-stability-keep-your-gunpowder-dry/ | ||
http://openwetware.org/wiki/Endy:Preparing_Antibiotic_Stocks | |||
ATCC Antibiotic concentration recommendations: | ATCC Antibiotic concentration recommendations: | ||
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http://hymanlab.mpi-cbg.de/hyman_lab/wp-content/uploads/2012/08/atcc_recommendations_antibiotic_concentrations.pdf | http://hymanlab.mpi-cbg.de/hyman_lab/wp-content/uploads/2012/08/atcc_recommendations_antibiotic_concentrations.pdf | ||
'''Mupirocin:''' http://en.wikipedia.org/wiki/Mupirocin | |||
'''Ampicillin:''' | '''Ampicillin:''' | ||
Degraded by B-lactamase (encoded by ''bla'') | |||
http://openwetware.org/wiki/Ampicillin | |||
CLP classification: http://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/cl-inventory/view-notification-summary/10942 | |||
'''Carbenicillin:''' | |||
*Also degraded by B-lactamase, but slower than Ampicillin. (http://bitesizebio.com/articles/whats-the-problem-with-ampicillin-selection/) | |||
*More expensive than ampicillin. | |||
'''Kanamycin:''' | '''Kanamycin:''' | ||
Capsule Formation is Necessary for Kanamycin Tolerance in | |||
Escherichia coli K12: http://www.microbiology.ubc.ca/sites/default/files/roles/drupal_ungrad/JEMI/17/05.1G.pdf | |||
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http://mbioblog.asm.org/mbiosphere/2013/05/resistance-to-last-line-antibiotic-also-makes-bacteria-resistant-to-immune-attacks.html | http://mbioblog.asm.org/mbiosphere/2013/05/resistance-to-last-line-antibiotic-also-makes-bacteria-resistant-to-immune-attacks.html | ||
'''Persistence in the face of antibiotics:''' | |||
http://www.sciencemag.org/content/334/6058/982 | |||
'''Lantibiotics:''' | |||
http://www.ncbi.nlm.nih.gov/pubmed/19393544 | |||
=Concepts= | |||
MIC | |||
PAE | |||
=Bibliography= | |||
Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules | |||
http://www.pnas.org/content/110/40/16169.abstract | |||
http://jac.oxfordjournals.org/content/54/1/139.full.pdf | |||
The unstructured domain of colicin N kills Escherichia coli: http://onlinelibrary.wiley.com/doi/10.1111/mmi.12260/abstract | |||
Latest revision as of 16:04, 15 August 2014
Notes and links regarding antibiotics:
http://gotsomescienceonyou.com/2013/08/06/resist-the-resistance/
http://openwetware.org/wiki/Fong:Antibiotics
http://bitesizebio.com/articles/antibiotic-stability-keep-your-gunpowder-dry/
http://openwetware.org/wiki/Endy:Preparing_Antibiotic_Stocks
ATCC Antibiotic concentration recommendations:
Mupirocin: http://en.wikipedia.org/wiki/Mupirocin
Ampicillin:
Degraded by B-lactamase (encoded by bla)
http://openwetware.org/wiki/Ampicillin
CLP classification: http://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/cl-inventory/view-notification-summary/10942
Carbenicillin:
- Also degraded by B-lactamase, but slower than Ampicillin. (http://bitesizebio.com/articles/whats-the-problem-with-ampicillin-selection/)
- More expensive than ampicillin.
Kanamycin:
Capsule Formation is Necessary for Kanamycin Tolerance in Escherichia coli K12: http://www.microbiology.ubc.ca/sites/default/files/roles/drupal_ungrad/JEMI/17/05.1G.pdf
Chloramphenicol:
- Inhibits protein translation by interfering with peptide bond formation.
Bibliography:
Designing Antibiotic Cycling Strategies by Determining and Understanding Local Adaptive Landscapes : http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056040
Persistence in the face of antibiotics:
http://www.sciencemag.org/content/334/6058/982
Lantibiotics:
http://www.ncbi.nlm.nih.gov/pubmed/19393544
Concepts
MIC
PAE
Bibliography
Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules http://www.pnas.org/content/110/40/16169.abstract
http://jac.oxfordjournals.org/content/54/1/139.full.pdf
The unstructured domain of colicin N kills Escherichia coli: http://onlinelibrary.wiley.com/doi/10.1111/mmi.12260/abstract
