Analyzing pooled sequenced data with selection Main project page
Previous entry

## Simulating evolution and then pooled sequencing

• We start with a population of N individuals with a certain SNP distribution $P(M) ~ N(\mu, \Sigma)$.

To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter).

• We then evolve the populations for g generations with recombination

To do this we can use Kessner's Forqs. Forqs allows the user to specify the recombination rate file. Which might be useful in the future.

• Simulate pooled sequencing