# User:Hussein Alasadi/Notebook/stephens/2013/10/16

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 Revision as of 00:16, 17 October 2013 (view source) (→Simulating evolution and then pooled sequencing)← Previous diff Revision as of 00:19, 17 October 2013 (view source) (→Simulating evolution and then pooled sequencing)Next diff → Line 8: Line 8: ==Simulating evolution and then pooled sequencing== ==Simulating evolution and then pooled sequencing== - * '''We start with a population of N individuals with a certain SNP distribution $P(M) \~ N(\mu, \Sigma)$.''' + * '''We start with a population of N individuals with a certain SNP distribution $P(M) \tilde N(\mu, \Sigma)$.''' To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter). To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter).

## Revision as of 00:19, 17 October 2013

Analyzing pooled sequenced data with selection Main project page
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## Simulating evolution and then pooled sequencing

• We start with a population of N individuals with a certain SNP distribution $P(M) \tilde N(\mu, \Sigma)$.

To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter).

• We then evolve the populations for g generations with recombination

To do this we can use Kessner's Forqs. Forqs allows the user to specify the recombination rate file. Which might be useful in the future.

• Simulate pooled sequencing