User:Hussein Alasadi/Notebook/stephens/2013/10/16

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==Entry title==
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==Simulating evolution and then pooled sequencing==
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* Insert content here...
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* '''We start with a population of N individuals with a certain SNP distribution <math> P(M) ~ N(\mu, \Sigma) </math>.'''
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To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter).
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* '''We then evolve the populations for g generations with recombination'''
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To do this we can use Kessner's [http://arxiv.org/abs/1310.3234 Forqs]. Forqs allows the user to specify the recombination rate file. Which might be useful in the future.
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* '''Simulate pooled sequencing'''
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Revision as of 00:16, 17 October 2013

Analyzing pooled sequenced data with selection Main project page
Previous entry      

Simulating evolution and then pooled sequencing

  • We start with a population of N individuals with a certain SNP distribution  P(M) ~ N(\mu, \Sigma) .

To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter).

  • We then evolve the populations for g generations with recombination

To do this we can use Kessner's Forqs. Forqs allows the user to specify the recombination rate file. Which might be useful in the future.

  • Simulate pooled sequencing





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