User:Holmesbr
From OpenWetWare
Brad Holmes
Laboratory of Molecular Genetics
6 Center Drive
NICHD, NIH
Bethesda, MD 20892
(username) AT mail DOT nih DOT gov
Hi! My name is Brad Holmes and I am Robert Crouch's lab in the LMG. We study RNase H1.
Research Interests
RNase H1
mtDNA replication
Education/Lab Experience
- B.S. in Biochemistry, Texas A&M University, 2004 Summa Cum Laude.
- Worked as an undergraduate researcher for two years and then as a post-bac for Jerry Tsai, studying protein structure prediction and homology modeling.
- Summer Undergraduate Reserach Fellow at UT Southwestern Medical Center. Worked for 10 weeks for Kevin Gardnerto implement a few software programs to automate the process of NMR data analysis.
Publications
- Parsons J, Holmes JB, Rojas JM, Tsai J, and Strauss CE. Practical conversion from torsion space to Cartesian space for in silico protein synthesis. J Comput Chem. 2005 Jul 30;26(10):1063-8. DOI:10.1002/jcc.20237 |
- Holmes JB and Tsai J. Characterizing conserved structural contacts by pair-wise relative contacts and relative packing groups. J Mol Biol. 2005 Dec 2;354(3):706-21. DOI:10.1016/j.jmb.2005.09.081 |
- Fischer TB, Holmes JB, Miller IR, Parsons JR, Tung L, Hu JC, and Tsai J. Assessing methods for identifying pair-wise atomic contacts across binding interfaces. J Struct Biol. 2006 Feb;153(2):103-12. DOI:10.1016/j.jsb.2005.11.005 |
- Holmes JB and Tsai J. Some fundamental aspects of building protein structures from fragment libraries. Protein Sci. 2004 Jun;13(6):1636-50. DOI:10.1110/ps.03494504 |