User:Tkadm30/Notebook/THC: Difference between revisions
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* Cannabis-derived cannabinoids are known as phytocannabinoids. | * Cannabis-derived cannabinoids are known as phytocannabinoids. | ||
* THC stimulate anandamide synthesis by binding to the CB1 receptor, thus producing a antidepressant and neuroprotective effect. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866040/ PMID] | * THC stimulate anandamide synthesis by binding to the CB1 receptor, thus producing a antidepressant and neuroprotective effect. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866040/ PMID] | ||
=== THC effect on hippocampal neurogenesis === | ===THC effect on hippocampal neurogenesis=== | ||
* Regulation of stress-induced neuroinflammation in the hippocampus. | * Regulation of stress-induced neuroinflammation in the hippocampus. | ||
* Hippocampal neurogenesis is enhanced. [http://www.ncbi.nlm.nih.gov/pubmed/16224541/ PMID] | * Hippocampal neurogenesis is enhanced. [http://www.ncbi.nlm.nih.gov/pubmed/16224541/ PMID] | ||
===Experimental=== | |||
* Synaptogenic effect of Δ9-THC/DHEA ligands promote hippocampal development. | * Synaptogenic effect of Δ9-THC/DHEA ligands promote hippocampal development. | ||
* Δ9-THC/DHEA ligands (synaptamide) affect neural stem/progenitor cells (NS/PC) proliferation in the hippocampus. | * Δ9-THC/DHEA ligands (synaptamide) affect neural stem/progenitor cells (NS/PC) proliferation in the hippocampus. | ||
=== References === | === References === | ||
# https://en.wikipedia.org/wiki/Tetrahydrocannabinol | # https://en.wikipedia.org/wiki/Tetrahydrocannabinol | ||
# https://en.wikipedia.org/wiki/Cannabinoid | # https://en.wikipedia.org/wiki/Cannabinoid | ||
Revision as of 04:44, 7 July 2015
- Tetrahydrocannabinol (THC) is the main psychoactive constituent of Cannabis sativa L (Marijuana) plant.
- Other Marijuana compounds includes Cannabichromene (CBC), Cannabidiol (CBD), Cannabinol (CBN), and Cannabigerol (CBG).
- Cannabis-derived cannabinoids are known as phytocannabinoids.
- THC stimulate anandamide synthesis by binding to the CB1 receptor, thus producing a antidepressant and neuroprotective effect. PMID
THC effect on hippocampal neurogenesis
- Regulation of stress-induced neuroinflammation in the hippocampus.
- Hippocampal neurogenesis is enhanced. PMID
Experimental
- Synaptogenic effect of Δ9-THC/DHEA ligands promote hippocampal development.
- Δ9-THC/DHEA ligands (synaptamide) affect neural stem/progenitor cells (NS/PC) proliferation in the hippocampus.
