User:Etienne Robillard/Notebook/Rhodopsin

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(Unresolved questions)
(Unresolved questions)
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== Unresolved questions ==
== Unresolved questions ==
# In the expression "'''blind as a bat'''", is the bat blindness a permanent or temporary phenomenon and '''how''' could you assert this is related to cGMP/ATP based phosphorylation of the Rhodopsin kinase?
# In the expression "'''blind as a bat'''", is the bat blindness a permanent or temporary phenomenon and '''how''' could you assert this is related to cGMP/ATP based phosphorylation of the Rhodopsin kinase?
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'''Answer''': Temporary! The bat can recover its vision if the GABA receptor is cleared from cAMP/ATP dependent competitive ligands, thus allowing GPCR based signal transduction to occur normally. [http://www.reactome.org/entitylevelview/PathwayBrowser.html#DB=gk_current&FOCUS_SPECIES_ID=48887&FOCUS_PATHWAY_ID=500792&ID=419426 1] Notice also that the S1PR4 gene is a '''near-neighboor''' of the Cannabinoid receptors!
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** '''Answer''': Temporary! The bat can recover its vision if the GABA receptor is cleared from cAMP/ATP dependent competitive ligands, thus allowing GPCR based signal transduction to occur normally. [http://www.reactome.org/entitylevelview/PathwayBrowser.html#DB=gk_current&FOCUS_SPECIES_ID=48887&FOCUS_PATHWAY_ID=500792&ID=419426 1] Notice also that the S1PR4 gene is a '''near-neighboor''' of the Cannabinoid receptors!
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Revision as of 20:30, 25 March 2013

References on Rhodopsin

Unresolved questions

  1. In the expression "blind as a bat", is the bat blindness a permanent or temporary phenomenon and how could you assert this is related to cGMP/ATP based phosphorylation of the Rhodopsin kinase?

Answer: Temporary! The bat can recover its vision if the GABA receptor is cleared from cAMP/ATP dependent competitive ligands, thus allowing GPCR based signal transduction to occur normally. 1 Notice also that the S1PR4 gene is a near-neighboor of the Cannabinoid receptors!

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