User:Etienne Robillard/Notebook/Piperidine

From OpenWetWare

< User:Etienne Robillard | Notebook
Revision as of 10:09, 8 November 2013 by Etienne Robillard (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
  • An important secondary amine used as precursor to alkylamines with a aryl-ketone (heteroarylalkyl) moeity when the reaction is performed in presence of a [cyanide anion] as the nitrogen substitution group .
  • In organic synthesis, piperidine may participate in hydrogenation of C=N double bounds where the N-substituted chiral imine center may be converted to a enamine, the tautomeric form of a imine. 1

Reductive alkylation of N-aryl substituted imines via piperidine-derived enamines

Piperidine derivatives in nucleophilic keto-enol (imine) substitutions

  • Notebook : AuNP(gold) catalyzed cyclic imide hydrolase
  • For DNA depurination with a 2-cyanoethyl hetero-aryl-alkyl moeity (ie: a N-methyl cyanide anion), see Ethanamine
  • For in situ polymer-based drug delivery of phenethylamine substituted imines, see Phenethylamine and Grignard reagents .

See also

Personal tools