User:Etienne Robillard/Notebook/Phenothiazine

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Is hemoglobin a catalyst for sulfoxidation of 2-phenyl-2-(2-piperidyl) acetic acid methyl ester?

Brainstorming

  • Transfère d'agents pharmaceutiques par compression adiabatique: 10.1016/j.ijms.2008.04.029 Une méthode d'accroitre l'adsorption moléculaires de drogue de synthèse (antidépressants) par oxidation de l'hemoglobin  ? Mot clés: Compréssion adiabatique, Aerosol thérapy, drug delivery, l-phenylalanine tert-butyl ester hydro-chloride, DMSO (dimethyl-sulfoxide), DCM (methylene chloride)
  • Voir aussi http://www.montefiore.ulg.ac.be/systems/GBIO/gbio001/chap_4.pdf
  • Active (pesticide) constituents : http://www.apvma.gov.au/products/constituents/standards/actives_definition.php
  • 10.1016/0006-2952(89)90132-9
  • Chlorpromazine:
    • must compare Chlorpromazine to Arylcyclohexylamine (ie: Ketamine)..
    • Although both drugs are prescribed for "schizophrenia", only Ketamine is the model to instigate the effects on the NMDA receptor.
    • Chlorpromazine might induces seizures and other crap which were not found in our current data set.

See also

http://en.wikipedia.org/wiki/Chlorpromazine

HRP (EC 1.11.1.7): http://chemwiki.ucdavis.edu/Biological_Chemistry/Catalysts/Case_Studies/Horseradish_Peroxidase

Arylcyclohexylamine

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