User:Tkadm30/Notebook/Paliperidone/2013/10/10: Difference between revisions
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# Establish Role of [http://www.uniprot.org/uniprot/Q06278 Aldehyde oxidase] in paliperidone metabolite degradation | # Establish Role of [http://www.uniprot.org/uniprot/Q06278 Aldehyde oxidase] in paliperidone metabolite degradation | ||
# Confirm degradation of metabolite vs no inhibitor (as for [[User:Etienne_Robillard/Notebook/Paliperidone/2013/06/21|PLP biosynthesis from 9-oh risperidone]]...) | # Confirm degradation of metabolite vs no inhibitor (as for [[User:Etienne_Robillard/Notebook/Paliperidone/2013/06/21|PLP biosynthesis from 9-oh risperidone]]...) | ||
# Study (Mg+ATP) | # Study (Mg+ATP) hydrolysis further | ||
## include notes about AU-bound metal catalysts, OPH '''hydrolase''' (AuNP hydrosols) | ## include notes about AU-bound metal catalysts, OPH '''hydrolase''' (AuNP hydrosols) | ||
## Take notes about serine hydrolase | |||
==See also== | ==See also== | ||
[[User:Etienne_Robillard/Notebook/OPH|OPH Notebook]] | [[User:Etienne_Robillard/Notebook/OPH|OPH Notebook]] |
Revision as of 12:39, 17 October 2013
9-OH (risperidone) degradation scrachpad
- Todo:
- Investigate CYP2D6
- Establish Role of Aldehyde oxidase in paliperidone metabolite degradation
- Confirm degradation of metabolite vs no inhibitor (as for PLP biosynthesis from 9-oh risperidone...)
- Study (Mg+ATP) hydrolysis further
- include notes about AU-bound metal catalysts, OPH hydrolase (AuNP hydrosols)
- Take notes about serine hydrolase