User:Etienne Robillard/Notebook/Paliperidone/2013/10/10

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(9-OH (risperidone) degradation scrachpad)
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# Establish Role of [http://www.uniprot.org/uniprot/Q06278 Aldehyde oxidase] in paliperidone metabolite degradation
# Establish Role of [http://www.uniprot.org/uniprot/Q06278 Aldehyde oxidase] in paliperidone metabolite degradation
# Confirm degradation of metabolite vs no inhibitor (as for [[User:Etienne_Robillard/Notebook/Paliperidone/2013/06/21|PLP biosynthesis from 9-oh risperidone]]...)
# Confirm degradation of metabolite vs no inhibitor (as for [[User:Etienne_Robillard/Notebook/Paliperidone/2013/06/21|PLP biosynthesis from 9-oh risperidone]]...)
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# Study (Mg+ATP) hydrolisis further  
+
# Study (Mg+ATP) hydrolysis further  
## include notes about AU-bound metal catalysts, OPH '''hydrolase''' (AuNP hydrosols)
## include notes about AU-bound metal catalysts, OPH '''hydrolase''' (AuNP hydrosols)
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## Take notes about serine hydrolase
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==See also==
==See also==
[[User:Etienne_Robillard/Notebook/OPH|OPH Notebook]]
[[User:Etienne_Robillard/Notebook/OPH|OPH Notebook]]

Revision as of 15:39, 17 October 2013

9-OH (risperidone) degradation scrachpad

  • Todo:
  1. Investigate CYP2D6
  2. Establish Role of Aldehyde oxidase in paliperidone metabolite degradation
  3. Confirm degradation of metabolite vs no inhibitor (as for PLP biosynthesis from 9-oh risperidone...)
  4. Study (Mg+ATP) hydrolysis further
    1. include notes about AU-bound metal catalysts, OPH hydrolase (AuNP hydrosols)
    2. Take notes about serine hydrolase

See also

OPH Notebook

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