User:Etienne Robillard/Notebook/Methylphenidate

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(Microwave/DMF activated N-benzylformamide catalysis of (R,R')-(+)-methylphenidate)
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Cycloalkane -> [[User:Etienne_Robillard/Notebook/Schiff_base|Schiff base]] -> benzylamine protected enantiomer (ie: methylphenidate...)
Cycloalkane -> [[User:Etienne_Robillard/Notebook/Schiff_base|Schiff base]] -> benzylamine protected enantiomer (ie: methylphenidate...)
-
=== Microwave/DMF activated N-benzylformamide catalysis of (R,R')-(+)-methylphenidate ===
+
=== Microwave/DMF activated N-benzylformamide catalysis of (R,R')-(+)-methylphenidate: a glycine-activated neural GABA antagonist ===
* 130605:  
* 130605:  
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** until the 5th of july is over, you may want to review the [http://www.kegg.jp/dbget-bin/www_bget?pathway+map00360 Shikimate pathway] :)
** until the 5th of july is over, you may want to review the [http://www.kegg.jp/dbget-bin/www_bget?pathway+map00360 Shikimate pathway] :)
** lovely:
** lovely:
-
** Science reality [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033428/ ?]  
+
** Science reality [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033428/ ?]
 +
* 130606:
 +
** Chuck:LOL really
 +
 
 +
** Chuck: FUCK
 +
 
 +
** Oracle: Dude, dont talk EVER to proper and finely educated ladies this way...
 +
 
 +
** Oracle: There '''must''' is a proper way to address the detention of peaceful civilian using '''non-violence'''...
 +
 
 +
** Chuck: They must be thinking i'm a f<CENSORED> schizophreniac now.
 +
 
 +
** Oracle: Yes. All the time. That not very interesting. Why are you asking all the times the same thing over and over again?
 +
 
 +
** Chuck: They made plans to put me in a detention camp and test on me [[User:Etienne_Robillard/Notebook/Paliperidone|lethal drugs]] and lithium for 3 years.
 +
 
 +
** Chuck: I don't like that. :(
 +
 
 +
** Oracle: Insanity is dangerous.
 +
 
 +
** Chuck: Especially when the purpose of this detention is to make me a chemical blue cheese. I love my sanity and my sweet kush. I don't want they're to be a fucking guinea pig for their human experiments
 +
with sulfonamides and shit.
 +
 
 +
** Oracle: Bastards. Don't let them make you a fucking lunatic. Be independent.
 +
 
 +
** Chuck: maybe worth trying some LSD next time. :)
 +
 
 +
** Oracle: mush ?
 +
 
 +
** Chuck: i love putting my Mushrooms in a soup! yay! :)
=== related documentation (possibly outdated) ===
=== related documentation (possibly outdated) ===
* [[DMF]]
* [[DMF]]

Revision as of 20:06, 6 July 2013

http://chemwiki.ucdavis.edu/Organic_Chemistry/Hydrocarbons/Alkanes/Nomenclature_of_Cycloalkanes

The Acetoacetic Ester Condensation (Claisen Condensation...)

United States Patent 8283472

http://en.wikipedia.org/wiki/Triethyl_orthoformate (note the cyanide mention at the top of the page...)

FRIEDEL-CRAFT acylation: http://www.chem.ucalgary.ca/courses/351/Carey5th/Ch12/ch12-7.html

4-methylimidazole (4-Mel) -> 4-acylaminopyridine derivative: US7998971

Construction of optically active (4-trans) methylphenidate hcl derivatives ! http://www.seattlepi.com/news/article/Group-finds-carcinogen-in-Pepsi-outside-Calif-4644602.php

GSK-3: glycogen synthase kinase 3 (inhibitor)


Never give up, never surrender

Cycloalkane -> Schiff base -> benzylamine protected enantiomer (ie: methylphenidate...)

Microwave/DMF activated N-benzylformamide catalysis of (R,R')-(+)-methylphenidate: a glycine-activated neural GABA antagonist

  • 130605:
    • doi: 10.1073/pnas.1005399107
    • until the 5th of july is over, you may want to review the Shikimate pathway :)
    • lovely:
    • Science reality ?
  • 130606:
    • Chuck:LOL really
    • Chuck: FUCK
    • Oracle: Dude, dont talk EVER to proper and finely educated ladies this way...
    • Oracle: There must is a proper way to address the detention of peaceful civilian using non-violence...
    • Chuck: They must be thinking i'm a f<CENSORED> schizophreniac now.
    • Oracle: Yes. All the time. That not very interesting. Why are you asking all the times the same thing over and over again?
    • Chuck: They made plans to put me in a detention camp and test on me lethal drugs and lithium for 3 years.
    • Chuck: I don't like that. :(
    • Oracle: Insanity is dangerous.
    • Chuck: Especially when the purpose of this detention is to make me a chemical blue cheese. I love my sanity and my sweet kush. I don't want they're to be a fucking guinea pig for their human experiments

with sulfonamides and shit.

    • Oracle: Bastards. Don't let them make you a fucking lunatic. Be independent.
    • Chuck: maybe worth trying some LSD next time. :)
    • Oracle: mush ?
    • Chuck: i love putting my Mushrooms in a soup! yay! :)

related documentation (possibly outdated)

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