User:Etienne Robillard/Notebook/Fmoc protected phenoxyalkylamine synthesis - Revision history

Etienne Robillard at 02:00, 12 March 2013

Etienne Robillard — Tue, 12 Mar 2013 02:00:30 GMT

←Older revision		Revision as of 02:00, 12 March 2013
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	alkylamines and synthesis with Fmoc protected reagents, including primary and secondary amines		alkylamines and synthesis with Fmoc protected reagents, including primary and secondary amines
	as organocatalysts for development of synthetic pharmaceutical compounds with an aryl moeity, hence		as organocatalysts for development of synthetic pharmaceutical compounds with an aryl moeity, hence
-	refered herein as N,N-substituted arylcyclohexylamines.	+	refered herein as N,N-substituted arylcyclohexylamines.

-	=== Microwave-activated peptide synthesis ===	+	=== Microwave(light)-activated peptide synthesis under 2.45 GHz microwave frequency ===

	* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.45 GHz.		* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.45 GHz.

Etienne Robillard: /* Keywords */

Etienne Robillard — Sat, 09 Feb 2013 16:55:25 GMT

Keywords

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	=== Keywords ===		=== Keywords ===

-	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin, 2.450, ghz, imine, dimer, tryptophane, PVOH, drug delivery, MIT~~, Langer~~, Boston Children Hospital, wireless, empathy, apathy, cognition, visual memory, learning, Robert Langer, MIT, Lanza, Holmes, mefloquine, [http://unknownjournal.wordpress.com/2010/10/06/▼-report-the-kochs-their-nazi-past-american-oil-the-foundation-of-republican-ideology/ Koch Institute],	+	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin, 2.450, ghz, imine, dimer, tryptophane, PVOH, drug delivery, MIT, Boston Children Hospital, wireless, empathy, apathy, cognition, visual memory, learning, Dr. Robert S. Langer, MIT, Lanza, Holmes, mefloquine, [http://unknownjournal.wordpress.com/2010/10/06/▼-report-the-kochs-their-nazi-past-american-oil-the-foundation-of-republican-ideology/ Koch Institute], [http://articles.timesofindia.indiatimes.com/2008-06-12/europe/27747119_1_life-saving-drugs-langer-star-trek-style Viterbi algorithm]

	=== References ===		=== References ===

Etienne Robillard: /* Keywords */

Etienne Robillard — Sat, 09 Feb 2013 14:13:54 GMT

Keywords

←Older revision		Revision as of 14:13, 9 February 2013
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	=== Keywords ===		=== Keywords ===

-	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin, 2.450, ghz, imine, dimer, tryptophane, PVOH, drug delivery, MIT, Langer, Boston Children Hospital, wireless, empathy, apathy, cognition, visual memory, learning, Robert Langer, MIT, Lanza, Holmes, mefloquine, ~~etc~~	+	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin, 2.450, ghz, imine, dimer, tryptophane, PVOH, drug delivery, MIT, Langer, Boston Children Hospital, wireless, empathy, apathy, cognition, visual memory, learning, Robert Langer, MIT, Lanza, Holmes, mefloquine, [http://unknownjournal.wordpress.com/2010/10/06/▼-report-the-kochs-their-nazi-past-american-oil-the-foundation-of-republican-ideology/ Koch Institute],

	=== References ===		=== References ===

Etienne Robillard at 13:09, 9 February 2013

Etienne Robillard — Sat, 09 Feb 2013 13:09:29 GMT

←Older revision		Revision as of 13:09, 9 February 2013
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	=== Keywords ===		=== Keywords ===

-	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin	+	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin, 2.450, ghz, imine, dimer, tryptophane, PVOH, drug delivery, MIT, Langer, Boston Children Hospital, wireless, empathy, apathy, cognition, visual memory, learning, Robert Langer, MIT, Lanza, Holmes, mefloquine, etc

	=== References ===		=== References ===

Etienne Robillard: Added Artemisinin to the list of keywords which may be related to genome-wide anti-malarial drug formation from mw-assisted catalysis

Etienne Robillard — Wed, 30 Jan 2013 10:54:48 GMT

Added Artemisinin to the list of keywords which may be related to genome-wide anti-malarial drug formation from mw-assisted catalysis

←Older revision		Revision as of 10:54, 30 January 2013
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	=== Keywords ===		=== Keywords ===

-	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter	+	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin

	=== References ===		=== References ===

Etienne Robillard: /* Keywords */

Etienne Robillard — Tue, 29 Jan 2013 17:08:36 GMT

Keywords

←Older revision		Revision as of 17:08, 29 January 2013
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	=== Keywords ===		=== Keywords ===

-	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL,	+	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter

	=== References ===		=== References ===

Etienne Robillard: /* Microwave-activated peptide synthesis */

Etienne Robillard — Tue, 29 Jan 2013 16:58:44 GMT

Microwave-activated peptide synthesis

←Older revision		Revision as of 16:58, 29 January 2013
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	=== Microwave-activated peptide synthesis ===		=== Microwave-activated peptide synthesis ===

-	* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.~~4 ghz~~.	+	* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.45 GHz.
	* In fact, most peoples are unaware this operating frequency can modulate Fmoc protected oligos by micro-wave thermal irradiation, thus a remote attacker may exploit this unregulated frequency range to trigger Fmoc-SPPS based orthogonal ligations of N-methyl rich peptides. [[http://www.faqs.org/patents/app/20100305182 1]]		* In fact, most peoples are unaware this operating frequency can modulate Fmoc protected oligos by micro-wave thermal irradiation, thus a remote attacker may exploit this unregulated frequency range to trigger Fmoc-SPPS based orthogonal ligations of N-methyl rich peptides. [[http://www.faqs.org/patents/app/20100305182 1]]
	* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis		* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
	* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis		* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
-	* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.~~4ghz~~ spectrum]	+	* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.45 GHz spectrum]
	* From gun control to wireless control, unregulation of the S-band frequency is not without risks of abuses from bioterrorists to develop dual-purposes, synthetic bioweapons: http://nanopatentsandinnovations.blogspot.se/2009/11/microwave-manufactures-semiconductor.html		* From gun control to wireless control, unregulation of the S-band frequency is not without risks of abuses from bioterrorists to develop dual-purposes, synthetic bioweapons: http://nanopatentsandinnovations.blogspot.se/2009/11/microwave-manufactures-semiconductor.html
		+	** '''"The microwave reactor operates at 2.45 GHz and can be adapted to a continuous flow or autosampler system. "'''

	=== Keywords ===		=== Keywords ===

Etienne Robillard: /* Microwave-activated peptide synthesis */

Etienne Robillard — Tue, 29 Jan 2013 16:46:42 GMT

Microwave-activated peptide synthesis

←Older revision		Revision as of 16:46, 29 January 2013
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	* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis		* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
	* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis		* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
-	* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.4ghz spectrum]	+	* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.4ghz spectrum]
		+	* From gun control to wireless control, unregulation of the S-band frequency is not without risks of abuses from bioterrorists to develop dual-purposes, synthetic bioweapons: http://nanopatentsandinnovations.blogspot.se/2009/11/microwave-manufactures-semiconductor.html
		+
	=== Keywords ===		=== Keywords ===

Etienne Robillard at 13:59, 26 January 2013

Etienne Robillard — Sat, 26 Jan 2013 13:59:39 GMT

←Older revision		Revision as of 13:59, 26 January 2013
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	* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis		* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
	* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis		* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
-		+	* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.4ghz spectrum]
	=== Keywords ===		=== Keywords ===

-	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines	+	N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL,

	=== References ===		=== References ===

Etienne Robillard: Added note to US patent 20100305182

Etienne Robillard — Sat, 26 Jan 2013 13:01:32 GMT

Added note to US patent 20100305182

←Older revision		Revision as of 13:01, 26 January 2013
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	* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.4 ghz.		* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.4 ghz.
		+	* In fact, most peoples are unaware this operating frequency can modulate Fmoc protected oligos by micro-wave thermal irradiation, thus a remote attacker may exploit this unregulated frequency range to trigger Fmoc-SPPS based orthogonal ligations of N-methyl rich peptides. [[http://www.faqs.org/patents/app/20100305182 1]]
	* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis		* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
	* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis		* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis