User:Etienne Robillard/Notebook/Fmoc protected phenoxyalkylamine synthesis

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The purpose of this page is to investigate the design and method of operation of novel psychotropic alkylamines and synthesis with Fmoc protected reagents, including primary and secondary amines as organocatalysts for development of synthetic pharmaceutical compounds with an aryl moeity, hence refered herein as N,N-substituted arylcyclohexylamines.

Microwave-activated peptide synthesis

• NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.4 ghz.
• http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
• http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis

Keywords

N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines

References

1. Rodríguez H, Suarez M, and Albericio F. . pmid:20127857. PubMed HubMed [Rodriguez-H-2012]
2. Ludwig M, Hoesl CE, Höfner G, and Wanner KT. . pmid:16675066. PubMed HubMed [Ludwig-M-Cornelia-E-CE-Hoesl-Klaus-T-KT-Wanner]

See also

• Lewis Acid Catalysed Pictet Spengler Formation of Substituted 1,2,3,4-Tetrahydroisoquinolines.