User:Etienne Robillard/Notebook/Fmoc protected phenoxyalkylamine synthesis

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* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.4 ghz.
* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.4 ghz.
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* In fact, most peoples are unaware this operating frequency can modulate Fmoc protected oligos by micro-wave thermal irradiation, thus a remote attacker may exploit this unregulated frequency range to trigger Fmoc-SPPS based orthogonal ligations of N-methyl rich peptides. [[http://www.faqs.org/patents/app/20100305182 1]]
* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
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* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.4ghz spectrum]
=== Keywords ===
=== Keywords ===
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N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines
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N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL,
=== References ===
=== References ===

Revision as of 08:59, 26 January 2013

The purpose of this page is to investigate the design and method of operation of novel psychotropic alkylamines and synthesis with Fmoc protected reagents, including primary and secondary amines as organocatalysts for development of synthetic pharmaceutical compounds with an aryl moeity, hence refered herein as N,N-substituted arylcyclohexylamines.

Contents

Microwave-activated peptide synthesis

Keywords

N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL,

References

  1. Rodríguez H, Suarez M, and Albericio F. . pmid:20127857. PubMed HubMed [Rodriguez-H-2012]
  2. Ludwig M, Hoesl CE, Höfner G, and Wanner KT. . pmid:16675066. PubMed HubMed [Ludwig-M-Cornelia-E-CE-Hoesl-Klaus-T-KT-Wanner]
All Medline abstracts: PubMed HubMed

See also

  • Lewis Acid Catalysed Pictet Spengler Formation of Substituted 1,2,3,4-Tetrahydroisoquinolines.
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