User:Tkadm30/Notebook/Endocannabinoids: Difference between revisions
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* http://www.ncbi.nlm.nih.gov/pubmed/21288475 | * http://www.ncbi.nlm.nih.gov/pubmed/21288475 | ||
* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661034/ | * http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661034/ | ||
* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773444/ | |||
Cannabinoids and hippocampal neurogenesis: | Cannabinoids and hippocampal neurogenesis: | ||
* http://www.truthonpot.com/2013/07/13/scientists-discover-another-way-marijuana-helps-the-brain-grow/ | * http://www.truthonpot.com/2013/07/13/scientists-discover-another-way-marijuana-helps-the-brain-grow/ |
Revision as of 06:14, 2 October 2014
Notes
Hypothesis
- DHA may potentiate synaptic plasticity (and cognition) via retrograde CB1 signaling.
Model
- Use omega 3 (DHA) fatty acids as substrate for docosahexaenoylethanolamide (DHEA) hydrolysis
- Protect the hippocampus and neurons from stress induced damage.
- CB1: A synaptogenic receptor
Documentation
Protocol:
- http://www.ncbi.nlm.nih.gov/pubmed/23103355
- http://www.ncbi.nlm.nih.gov/pubmed/11470906
- http://www.ncbi.nlm.nih.gov/pubmed/9842734/
- http://www.ncbi.nlm.nih.gov/pubmed/15111006/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035504/
- http://www.ncbi.nlm.nih.gov/pubmed/22959887
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/
- http://www.ncbi.nlm.nih.gov/pubmed/21288475
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661034/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773444/
Cannabinoids and hippocampal neurogenesis:
- http://www.truthonpot.com/2013/07/13/scientists-discover-another-way-marijuana-helps-the-brain-grow/
DHA:
Anandamide signaling:
FAAH (fatty acid amide hydrolase):
Introduction to fatty amides:
Synaptic Plasticity:
Keywords
hippocampus, anandamide, FAAH, fatty acids, THC, neurogenesis, synaptogenesis