User:Tkadm30/Notebook/Endocannabinoids: Difference between revisions
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* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/ | * http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/ | ||
* http://www.ncbi.nlm.nih.gov/pubmed/21288475 | * http://www.ncbi.nlm.nih.gov/pubmed/21288475 | ||
* Cannabinoids and hippocampal neurogenesis: http://www.truthonpot.com/2013/07/13/scientists-discover-another-way-marijuana-helps-the-brain-grow/ | * http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661034/ | ||
Cannabinoids and hippocampal neurogenesis: | |||
* http://www.truthonpot.com/2013/07/13/scientists-discover-another-way-marijuana-helps-the-brain-grow/ | |||
DHA: | |||
* http://www.ncbi.nlm.nih.gov/pubmed/19682204 | |||
Anandamide signaling: | |||
* http://www.hindawi.com/journals/ije/2013/361895/ | |||
FAAH (fatty acid amide hydrolase): | |||
* http://www.brenda-enzymes.org/php/result_flat.php4?ecno=3.5.1.99 | |||
Introduction to fatty amides: | |||
* http://lipidlibrary.aocs.org/Lipids/amides/index.htm | |||
Synaptic Plasticity: | |||
* http://neuroscience.uth.tmc.edu/s1/chapter07.html | |||
=== Keywords === | === Keywords === | ||
hippocampus, anandamide, FAAH, fatty acids, THC, neurogenesis, synaptogenesis | hippocampus, anandamide, FAAH, fatty acids, THC, neurogenesis, synaptogenesis |
Revision as of 05:46, 2 October 2014
Notes
Hypothesis
- DHA may potentiate synaptic plasticity (and cognition) via retrograde CB1 signaling.
Model
- Use omega 3 (DHA) fatty acids as substrate for docosahexaenoylethanolamide (DHEA) hydrolysis
- Protect the hippocampus and neurons from stress induced damage.
- CB1: A synaptogenic receptor
Documentation
Protocol:
- http://www.ncbi.nlm.nih.gov/pubmed/23103355
- http://www.ncbi.nlm.nih.gov/pubmed/11470906
- http://www.ncbi.nlm.nih.gov/pubmed/9842734/
- http://www.ncbi.nlm.nih.gov/pubmed/15111006/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035504/
- http://www.ncbi.nlm.nih.gov/pubmed/22959887
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/
- http://www.ncbi.nlm.nih.gov/pubmed/21288475
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661034/
Cannabinoids and hippocampal neurogenesis:
- http://www.truthonpot.com/2013/07/13/scientists-discover-another-way-marijuana-helps-the-brain-grow/
DHA:
Anandamide signaling:
FAAH (fatty acid amide hydrolase):
Introduction to fatty amides:
Synaptic Plasticity:
Keywords
hippocampus, anandamide, FAAH, fatty acids, THC, neurogenesis, synaptogenesis