User:Tkadm30/Notebook/Endocannabinoids: Difference between revisions

Revision as of 07:53, 27 September 2014

DHA induced FAAH hydrolysis may promote synaptogenesis via CB1 activation.

Use omega 3 (DHA) fatty acids as substrate for docosahexaenoylethanolamide (DHEA) hydrolysis
Protect the hippocampus and neurons from stress induced damage.

Protocol:

CB1 signaling and memory:

DHA:

Anandamide signaling:

FAAH (fatty acid amide hydrolase):

Introduction to fatty amides:

hippocampus, anandamide, FAAH, fatty acids, THC, neurogenesis, synaptogenesis

@@ Line 1: / Line 1: @@
 __TOC__
-=== Creating anandamide ligands with polyunsaturated fatty acids and cannabinoids (THC) ===
+== Notes ==
-=== Experiment ===
+=== Hypothesis ===
-# Observe the properties and chemical reactions of hydrolysis of anandamide ligands in situ.
+DHA induced FAAH hydrolysis may promote synaptogenesis via CB1 activation.
-# measure blah blah blah
-=== Design ===
+=== Model ===
-# Use omega 3 (DHA) fatty acids as substrate for anandamide hydrolysis
+# Use omega 3 (DHA) fatty acids as substrate for docosahexaenoylethanolamide (DHEA) hydrolysis
 # Protect the hippocampus and neurons from stress induced damage.
@@ Line 18: / Line 17: @@
 * http://www.ncbi.nlm.nih.gov/pubmed/15111006/
 * http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/
+* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035504/
+* http://www.ncbi.nlm.nih.gov/pubmed/22959887
+* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/
 CB1 signaling and memory:
 * http://www.ncbi.nlm.nih.gov/pubmed/24648181
@@ Line 33: / Line 34: @@
 === Keywords ===
-hippocampus, anandamide, FAAH, fatty acids, THC, neurogenesis
+hippocampus, anandamide, FAAH, fatty acids, THC, neurogenesis, synaptogenesis